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VERSION:2.0
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METHOD:PUBLISH
BEGIN:VEVENT
DTSTAMP:20260612T114557Z
UID:https://www.mr.mpg.de/events/22413/10694
DTSTART:20191119T100000Z
DTEND:20191119T110000Z
CLASS:PUBLIC
CREATED:20191104T142458Z
DESCRIPTION: The detection of spectroscopically silent analytes in water is
  often accomplished by utilization of reactive probes that form chromophor
 ic analyte-dye conjugates. Unfortunately\, similar but distinctly differen
 t analytes usually do not provide unique spectroscopic features\, such tha
 t chromatographic separation steps have to be employed\, causing significa
 nt additional costs and hinder applications. Supramolecular indicator-dye 
 displacement assays can overcome certain limitations of reactive-probes\, 
 <i>e.g.</i>\, they allow for an <i>in situ</i> detection of even non-funct
 ionalizable analytes and are of great utility for reaction monitoring. How
 ever\, their analyte differentiation capabilities are again restricted. He
 re\, we present new strategies involving supramolecular sensing ensembles 
 that allow for improved analyte differentiation through spectroscopic fing
 erprints. We show that this strategy is applicable to both non-covalent an
 alyte-receptor binding schemes and to reactive-probe assays. As opposed to
  contemporary sensing strategies\, our approach capitalizes on induced spe
 ctroscopic changes that are resulting from\, (A) the direct “communicati
 on” of the analyte with a suitable reporter dye in a confined receptor c
 avity\, or (B) from the analyte-induced structural changes of supramolecul
 ar dye-aggregates\, leading to an altered dye-dye “communication”.
LAST-MODIFIED:20191104T142500Z
LOCATION:MPI for Medical Research\, Room: Seminar Room C
ORGANIZER;CN=Dr. Elisa D'Este:mailto:Elisa.Deste@mr.mpg.de
SUMMARY:ON Departmental Seminar with Frank Biedermann (KIT) on 'Supramolecu
 lar Sensing Ensembles: More Information through Communication': ON Departm
 ental Seminar with Frank Biedermann (KIT) on 'Supramolecular Sensing Ensem
 bles: More Information through Communication'
URL;VALUE=URI:https://www.mr.mpg.de/events/22413/10694
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