Publications of Karin Fritz-Wolf

Fritz-Wolf, K.; Urig, S.; Becker, K.: The structure of human thioredoxin reductase 1 provides insights into C-terminal rearrangements during catalysis. Journal of Molecular Biology (London) 370 (1), pp. 116 - 127 (2007)

Bauer, H.; Fritz-Wolf, K.; Winzer, A.; Kühner, S.; Little, S.; Yardley, V.; Vezin, H.; Palfey, B.; Schirmer, R. H.; Davioud−Charvet, E.: A fluoro analogue of the menadione derivative 6-[2'-(3'-methyl)-1',4'-naphthoquinolyl]hexanoic acid is a suicide substrate of glutathione reductase. Crystal structure of the alkylated human enzyme. Journal of the American Chemical Society 128 (33), pp. 10784 - 10794 (2006)

Urig, S.; Fritz-Wolf, K.; Réau, R.; Herold-Mende, C.; Tóth, K.; Davioud-Charvet, E.; Becker, K.: Gold(I)-Phosphinkomplexe für die irreversible Hemmung von humanen Disulfid-Reduktasen. Angewandte Chemie 118 (12), pp. 1915 - 1920 (2006)

Urig, S.; Fritz-Wolf, K.; Réau, R.; Herold-Mende, C.; Tóth, K.; Davioud-Charvet, E.; Becker, K.: Undressing of phosphine gold(I) complexes as irreversible inhibitors of human disulfide reductases. Angew. Chem. Internat. Ed. 45 (12), pp. 1881 - 1886 (2006)

Hiller, N.; Fritz-Wolf, K.; Deponte, M.; Wende, W.; Zimmermann, H.; Becker, K.: Plasmodium falciparum glutathione S-transferase — structural and mechanistic studies on ligand binding and enzyme inhibition. Protein Science 15 (2), pp. 281 - 289 (2006)

Urig, S.; Lieske, J.; Fritz-Wolf, K.; Irmler, A.; Becker, K.: Truncated mutants of human thioredoxin reductase 1 do not exhibit glutathione reductase activity. FEBS Letters 580 (15), pp. 3595 - 3600 (2005)

Deponte, M.; Urig, S.; Arscott, L. D.; Fritz-Wolf, K.; Réau, R.; Herold-Mende, C.; Koncarevic, S.; Meyer, M.; Davioud-Charvet, E.; Ballou, D. P. et al.; Williams, Jr., C. H.; Becker, K.: Mechanistic studies on a novel, highly potent gold-phosphole inhibitor of human glutathione reductase. The Journal of Biological Chemistry 280 (21), pp. 20628 - 20637 (2005)

Fritz-Wolf, K.; Becker, A.; Rahlfs, S.; Harwaldt, P.; Schirmer, R. H.; Kabsch, W.; Becker, K.: X-ray structure of glutathione S-transferase from the malarial parasite Plasmodium falciparum. Proceedings of the National Academy of Sciences of the United States of America 100 (24), pp. 13821 - 13826 (2003)

Fritz-Wolf, K.; Koller, K.-P.; Lange, G.; Liesum, A.; Sauber, K.; Schreuder, H.; Aretz, W.; Kabsch, W.: Structure-based prediction of modifications in glutarylamidase to allow single-step enzymatic production of 7-aminocephalosporanic acid from cephalosporin C. Protein Science 11 (1), pp. 92 - 103 (2002)

Eder, M.; Fritz-Wolf, K.; Kabsch, W.; Wallimann, T.; Schlattner, U.: Crystal structure of human ubiquitous mitochondrial creatine kinase. Proteins: Structure, Function, and Bioinformatics 39 (3), pp. 216 - 225 (2000)

Eder, M.; Schlattner, U.; Becker, A.; Wallimann, T.; Kabsch, W.; Fritz-Wolf, K.: Crystal structure of brain-type creatine kinase at 1.41 Å resolution. Protein Science 8 (11), pp. 2258 - 2269 (1999)

Becker, A.; Fritz-Wolf, K.; Kabsch, W.; Knappe, J.; Schultz, S.; Wagner, A. F. V.: Structure and mechanism of the glycyl radical enzyme pyruvate formate-lyase. Nature structural biology 6 (10), pp. 969 - 975 (1999)

Schlattner, U.; Forstner, M.; Eder, M.; Stachowiak, O.; Fritz-Wolf, K.; Wallimann, T.: Functional aspects of the X-ray structure of mitochondrial creatine kinase: a molecular physiology approach. Molecular and Cellular Biochemistry 184 (1-2), pp. 125 - 140 (1998)

Kabsch, W.; Fritz-Wolf, K.: Mitochondrial creatine kinase - a square protein. Current Opinion in Structural Biology 7 (6), pp. 811 - 818 (1997)

Fritz-Wolf, K.; Schnyder, T.; Wallimann, T.; Kabsch, W.: Structure of mitochondrial creatine kinase. Nature 381, pp. 341 - 345 (1996)

Scheffzek, K.; Klebe, C.; Fritz-Wolf, K.; Kabsch, W.; Wittinghofer, A.: Crystal structure of the nuclear Ras-related protein Ran in its GDP-bound form. Nature 374 (6520), pp. 378 - 381 (1995)

Fritz-Wolf, K.; Adler, H.; Göbel, U.; Zimmermann, H.; Becker, K.; Schirmer, H.: Is methylene blue a prodrug of azure b? In: Flavins and Flavoproteins 2011, pp. 547 - 550. Lulu.com, Raleigh, NC USA (2013)

Meissner, P.; Adler, H.; Kasozi, D.; Fritz-Wolf, K.; Schirmer, R. H.: The reducing milieu of parasitized cells as a target of antimalarial agents: Methylene blue as an ethical drug. In: Apicomplexan Parasites, pp. 115 - 136 (Ed. Becker, K.). Wiley-VCH, Weinheim (2011)

Jortzik, E.; Urig , S.; Fritz-Wolf, K.; Becker, K.: Human thioredoxin reductase − structural and mechanistic characteristics of an anticancer drug target. In: Flavins and flavoproteins 2008: Proceedings of the 16th international symposium, Jaca, Spain, June 8-13, 2008, pp. 333 - 338 (Ed. Frago, S.). Selbstverl., Zaragoza (2008)

Koncarevic, S.; Deponte, M.; Fritz-Wolf, K.; Meyer, M.; Urig, S.; Fischer, M.; Réau, R.; Davioud-Charvet, E.; Becker, K.: Mass spectrometic analysis of human glutathione reductase modified by a gold-phosphole inhibitor. In: Flavins and flavoproteins 2005: Proceedings of the 15th international symposium, Shonan Village, Japan, 17th - 22nd April, 2005, pp. 325 - 330 (Ed. Nishino, T.). Selbstverl., Shonan Village (2005)