Publications of Alfred Wittinghofer
All genres
Journal Article (87)
41.
Journal Article
273 (2), pp. 311 - 316 (1991)
Identification of valine/leucine/isoleucine and threonine/alanine/glycine proton-spin systems of Escherichia coli adenylate kinase by selective deuteration and selective protonation. Biochemical Journal 42.
Journal Article
266 (26), pp. 17700 - 17706 (1991)
p21 with a phenylalanine 28----leucine mutation reacts normally with the GTPase activating protein GAP but nevertheless has transforming properties. The Journal of Biological Chemistry 43.
Journal Article
29 (48), p. 10864 - 10864 (1990)
Fluorescence and NMR investigations on the ligand binding properties of adenylate kinases [Erratum to document cited in CA113(9):73603k]. Biochemistry 44.
Journal Article
29 (32), pp. 7451 - 7459 (1990)
Structurally and catalytically important residues in the phosphate binding loop of adenylate kinase of Escherichia coli. Biochemistry 45.
Journal Article
29 (32), pp. 7440 - 7450 (1990)
Fluorescence and NMR investigations on the ligand binding properties of adenylate kinases. Biochemistry 46.
Journal Article
62 (3), pp. 539 - 548 (1990)
Three-dimensional structures of H-ras p21 mutants: molecular basis for their inability to function as signal switch molecules. Cell 47.
Journal Article
345 (6273), pp. 309 - 315 (1990)
Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis. Nature 48.
Journal Article
265 (11), pp. 6353 - 6359 (1990)
Guanine nucleotide binding properties of the mammalian RalA protein produced in Escherichia coli. Journal of Biological Chemistry 49.
Journal Article
29 (2), pp. 504 - 511 (1990)
Proton NMR studies of transforming and nontransforming H-ras p21 mutants. Biochemistry 50.
Journal Article
86 (20), pp. 7687 - 7690 (1989)
Biochemical and crystallographic characterization of a complex of c-Ha-ras p21 and caged GTP with flash photolysis. Proceedings of the National Academy of Sciences of the United States of America 51.
Journal Article
341 (6239), pp. 209 - 214 (1989)
Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation. Nature 52.
Journal Article
264 (22), pp. 13086 - 13092 (1989)
C-terminal truncation of p21H preserves crucial kinetic and structural properties. The Journal of Biological Chemistry 53.
Journal Article
264 (14), pp. 8107 - 8112 (1989)
Structural and catalytic role of arginine 88 in Escherichia coli adenylate kinase as evidenced by chemical modification and site-directed mutagenesis. The Journal of Biological Chemistry 54.
Journal Article
207 (1), pp. 151 - 162 (1989)
Adenylate kinases from thermosensitive Escherichia coli strains. Journal of Molecular Biology (London) 55.
Journal Article
206 (1), pp. 257 - 259 (1989)
Crystallization and preliminary X-ray analysis of the human c-H-ras-oncogene product p21 complexed with GTP analogues. Journal of Molecular Biology (London) 56.
Journal Article
11 (3-4), pp. 203 - 209 (1989)
NMR studies of protein-nucleotide interactions: p21 and adenylate kinase. Bulletin of Magnetic Resonance 57.
Journal Article
27 (13), pp. 4735 - 4740 (1988)
Spectroscopic and hydrodynamic studies reveal structural differences in normal and transforming H-ras gene products. Biochemistry 58.
Journal Article
27 (13), pp. 4712 - 4720 (1988)
Mutations in the nucleotide binding loop of adenylate kinase of Escherichia coli. Biochemistry 59.
Journal Article
200 (4), pp. 745 - 748 (1988)
Proton-nuclear magnetic resonance studies of the aromatic spin systems of Escherichia coli adenylate kinase. Journal of Molecular Biology (London) 60.
Journal Article
150 (1), pp. 444 - 448 (1988)
Proton NMR studies of the GDP.Mg2+ complex of the Ha-ras oncogene product p21. Biochemical and Biophysical Research Communications