Rudolf Mößbauer Colloquium with Lars Steinmetz (Stanford University)

Lars Steinmetz will give a talk on ”Engineering Genomes Cell by Cell and Nucleotide by Nucleotide”.

We are delighted to welcome Lars Steinmetz to our institute and cordially invite all interested parties to attend his talk in person.

It is also possible to join his talk online via Zoom (registration required):

https://us06web.zoom.us/j/85354250110?pwd=aak0I0lBwvETaN3BPyV2JfZQ2bMHCm.1

The abstract of his talk is as follows:

Our lab develops genomic technologies to study the genetic basis of complex phenotypes, the mechanisms of gene regulation, and the molecular systems underpinning disease. As the basis for all our research, we are passionate about developing genomic technologies which increase the scale of biological questions that we can tackle. We’ve led innovations in therapeutic CRISPR genome editing, image-enabled cell sorting-based genetic screening, and single-cell multi-omics analyses. We’re exploring the frontiers of synthetic biology: using synthetic mitochondria we’re enhancing our understanding of genome architecture and transcriptional mechanisms, while exploring the therapeutic potential of genome re-engineering. We’re applying these technologies to study human diseases, like dilated cardiomyopathy and mitochondrial disorders, as well as developing biosensors for early diagnosis and intervention. Our ultimate goal is to leverage biological insights across scales to predict, diagnose, treat, and ultimately prevent disease.