Publikationen von Ilme Schlichting

Wu, Y. I.; Frey, D.; Lungu, O. I.; Jaehrig, A.; Schlichting, I.; Kuhlman, B.; Hahn, K. M.: A genetically encoded photoactivatable Rac controls the motility of living cells. Nature 461 (7260), S. 104 - 108 (2009)

Glas, A. F.; Maul, M. J.; Cryle, M.; Barends, T.; Schneider, S.; Kaya, E.; Schlichting, I.; Carell, T.: The archaeal cofactor F0 is a light-harvesting antenna chromophore in eukaryotes. Proceedings of the National Academy of Sciences of the United States of America 106 (28), S. 11540 - 11545 (2009)

Barends, T.; Hartmann, E.; Griese, J.; Beitlich, T.; Kirienko, N. V.; Ryjenkov, D. A.; Reinstein, J.; Shoeman, R. L.; Gomelsky, M.; Schlichting, I.: Structure and mechanism of a bacterial light-regulated cyclic nucleotide phosphodiesterase. Nature 459 (7249), S. 1015 - 1018 (2009)

Aldag, C.; Gromov, I. A.; Garcia-Rubio, I.; von König, K.; Schlichting, I.; Jaun, B.; Hilvert, D.: Probing the role of the proximal heme ligand in cytochrome P450cam by recombinant incorporation of selenocysteine. Proceedings of the National Academy of Sciences of the United States of America 106 (14), S. 5481 - 5486 (2009)

Novak, W. R. P.; Moulin, A. G.; Blakeley, M. P.; Schlichting, I.; Petsko, G. A.; Ringe, D.: A preliminary neutron diffraction study of γ-chymotrypsin. Acta Crystallographica Section F: Structural Biology and Crystallization Communications 65 (3), S. 317 - 320 (2009)

Maul, M. J.; Barends, T.; Glas, A. F.; Cryle, M.; Domratcheva, T.; Schneider, S.; Schlichting, I.; Carell, T.: Crystal structure and mechanism of a DNA (6-4) photolyase. Angewandte Chemie International Edition: a journal of the Gesellschaft Deutscher Chemiker 47 (52), S. 10076 - 10080 (2008)

Tyagi, A.; Penzkofer, A.; Griese, J.; Schlichting, I.; Kirienko, N. V.; Gomelsky, M.: Photodynamics of blue-light-regulated phosphodiesterase BlrP1 protein from Klebsiella pneumoniae and its photoreceptor BLUF domain. Chemical Physics Letters 354 (1), S. 130 - 141 (2008)

Cryle, M.; Schlichting, I.: Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex. Proceedings of the National Academy of Sciences of the United States of America 105 (41), S. 15696 - 15701 (2008)

Barends, T.; Dunn, M. F.; Schlichting, I.: Tryptophan synthase, an allosteric molecular factory. Current Opinion in Chemical Biology 12 (5), S. 593 - 600 (2008)

Chen, H.; Hirao, H.; Derat, E.; Schlichting, I.; Shaik, S.: Quantum mechanical/molecular mechanical study on the mechanisms of compound I formation in the catalytic cycle of chloroperoxidase: an overrview on heme Enzymes. Journal of Physical Chemistry B 112 (31), S. 9490 - 9500 (2008)

Kühnel, K.; Ke, N.; Cryle, M.; Sligar, S. G.; Schuler, M. A.; Schlichting, I.: Crystal structures of substrate-free and retinoic acid-bound cyanobacterial cytochrome P450 CYP120A1. Biochemistry 47 (25), S. 6552 - 6559 (2008)

Dunn, M. F.; Niks, D.; Ngo, H.; Barends, T.; Schlichting, I.: Tryptophan synthase: the workings of a channeling nanomachine. Trends in biochemical sciences 33 (6), S. 254 - 264 (2008)

Domratcheva, T.; Grigorenko, B. L.; Schlichting, I.; Nemukhin, A. V.: Molecular models predict light-induced glutamine tautomerization in BLUF photoreceptors. Biophysical Journal 94 (10), S. 3872 - 3879 (2008)

Barends, T.; Domratcheva, T.; Kulik, V.; Blumenstein, L.; Niks, D.; Dunn, M. F.; Schlichting, I.: Structure and mechanistic implications of a tryptophan synthase quinonoid intermediate. ChemBioChem: A European Journal of Chemical Biology 9 (7), S. 1024 - 1028 (2008)

Blumenstein, L.; Domratcheva, T.; Niks, D.; Ngo, H.; Seidel, R.; Dunn, M. F.; Schlichting, I.: BetaQ114N and betaT110V mutations reveal a critically important role of the substrate alpha-carboxylate site in the reaction specificity of tryptophan synthase. Biochemistry 46 (49), S. 14100 - 14116 (2007)

Makris, T. M.; von König, K.; Schlichting, I.; Sligar, S. G.: Alteration of P450 distal pocket solvent leads to impaired proton delivery and changes in heme geometry. Biochemistry 46 (49), S. 14129 - 14140 (2007)

Casino, P.; Niks, D.; Ngo, H.; Pan, P.; Brzovic, P.; Blumenstein, L.; Barends, T.; Schlichting, I.; Dunn, M. F.: Allosteric regulation of tryptophan synthase channeling: the internal aldimine probed by trans-3-indole-3'-acrylate binding. Biochemistry 46 (26), S. 7728 - 7739 (2007)

Ngo, H.; Harris, R.; Kimmich, N.; Casino, P.; Niks, D.; Blumenstein, L.; Barends, T.; Kulik, V.; Weyand, M.; Schlichting, I. et al.; Dunn, M. F.: Synthesis and characterization of allosteric probes of substrate channeling in the tryptophan synthase bienzyme complex. Biochemistry 46 (26), S. 7713 - 7727 (2007)

Ngo, H.; Kimmich, N.; Harris, R.; Niks, D.; Blumenstein, L.; Kulik, V.; Barends, T.; Schlichting, I.; Dunn, M. F.: Allosteric regulation of substrate channeling in tryptophan synthase: modulation of the L-serine reaction in stage I of the beta-reaction by alpha-site ligands. Biochemistry 46 (26), S. 7740 - 7753 (2007)

Kühnel, K.; Derat, E.; Terner, J.; Shaik, S.; Schlichting, I.: Structure and quantum chemical characterization of chloroperoxidase compound 0, a common reaction intermediate of diverse heme enzymes. Proceedings of the National Academy of Sciences of the United States of America 104 (1), S. 99 - 104 (2007)