Suchergebnisse

Eltokhi, A.; Gonzalez-Lozano, M. A.; Oettl, L.-L.; Rozov, A.; Pitzer, C.; Röth, R.; Berkel, S.; Hüser, M.; Harten, A.; Kelsch, W. et al.; Smit, A. B.; Rappold, G. A.; Sprengel, R.: Imbalanced post- and extrasynaptic SHANK2A functions during development affect social behavior in SHANK2-mediated neuropsychiatric disorders. Molecular Psychiatry 20221, S. 1 - 23 (2021)

Bertocchi, I.; Eltokhi, A.; Rozov, A.; Chi, V. N.; Jensen, V.; Bus, T.; Pawlak, V.; Serafino, M.; Sonntag, H.; Yang, B. et al.; Burnashev, N.; Li, S.-B.; Obenhaus, H. A.; Both, M.; Niewoehner, B.; Single, F. N.; Briese, M.; Boerner, T.; Gass, P.; Rawlins, J. N. P.; Köhr, G.; Bannerman, D. M.; Sprengel, R.: Voltage-independent GluN2A-type NMDA receptor Ca2+ signaling promotes audiogenic seizures, attentional and cognitive deficits in mice. Communications Biology 4, 59 (2021), S. 1 - 21 (2021)

Austen, J. M.; Pickering, C.; Sprengel, R.; Sanderson, D. J.: Dissociating representations of time and number in reinforcement-rate learning by deletion of the GluA1 AMPA receptor subunit in mice. Psychological Science, 956797620960392, S. 1 - 14 (2021)

Austen, J. M.; Sprengel, R.; Sanderson, D. J.: The GluA1 AMPAR subunit is necessary for hedonic responding but not hedonic value in female mice. Physiology & Behavior 228 (1), 113206, S. 1 - 7 (2021)

Eltokhi, A.; Santuy, A.; Merchan-Perez, A.; Sprengel, R.: Glutamatergic dysfunction and synaptic ultrastructural alterations in schizophrenia and autism spectrum disorder: evidence from human and rodent studies. International Journal of Molecular Sciences 22 (1), 59, S. 1 - 26 (2020)

Tang, W.; Zillmann, U.; Sprengel, R.: Alternative anesthesia of neonatal mice for global rAAV delivery in the brain with non-detectable behavioral interference in adults. Frontiers in Behavioral Neuroscience 14, 115, S. 1 - 10 (2020)

Bojarskaite, L.; Bjørnstad, D. M.; Pettersen, K. H.; Cunen, C.; Hermansen, G. H.; Åbjørsbråten, K. S.; Chambers, A. R.; Sprengel, R.; Vervaeke, K.; Tang, W. et al.; Enger, R.; Nagelhus, E. A.: Astrocytic Ca2+ signaling is reduced during sleep and is involved in the regulation of slow wave sleep. Nature Communications 11, 3240 (2020), S. 1 - 16 (2020)

Rappold, G. A.; Sprengel, R.: Heterogenität SHANK2-bedingter neuropsychiatrischer Störungen. Biospektrum 26, S. 11 - 15 (2020)

Schwenk, J.; Boudkkazi, S.; Kocylowski, M. K.; Brechet, A.; Zolles, G.; Bus, T.; Costa, K.; Kollewe, A.; Jordan, J.; Bank, J. et al.; Bildl, W.; Sprengel, R.; Kulik, A.; Roeper, J.; Schulte, U.; Fakler, B.: An ER assembly line of AMPA-receptors controls excitatory neurotransmission and its plasticity. Neuron 104 (4), e9, S. 680 - 692 (2019)

Enger, R.; Sprengel, R.; Nagelhus, E. A.; Tang, W.: Multiphoton Ca2+ imaging of astrocytes with genetically encoded indicators delivered by a viral approach. Multiphoton Microscopy, S. 251 - 277 (2019)

Hasan, M. T.; Althammer, F.; da Gouveia , M. S.; Goyon , S.; Eliava, M.; Lefevre , A.; Kerspern , D.; Schimmer , J.; Raftogianni, A.; Wahis , J. et al.; Knobloch, S.; Tang , Y.; Liu , X.; Jain, A.; Chavant , V.; Goumon , Y.; Weislogel , J.-M.; Hurlemann , R.; Herpertz , S. C.; Pitzer , C.; Darbon , P.; Dogbevia, G.; Bertocchi, I.; Larkum, M. E.; Sprengel, R.; Bading , H.; Charlet , A.; Grinevich, V.: A fear memory engram and its plasticity in the hypothalamic oxytocin system. Neuron 103 (1), S. 133 - 146 (2019)

Bygrave, A. M.; Jahans-Price, T.; Wolff, A. R.; Sprengel, R.; Kullmann, D. M.; Bannerman, D. M.; Kätzel, D.: Hippocampal–prefrontal coherence mediates working memory and selective attention at distinct frequency bands and provides a causal link between schizophrenia and its risk gene GRIA1. Translational Psychiatry 9, 142 (2019), S. 1 - 16 (2019)

Aitta-aho, T.; Maksimovic, M.; Dahl, K.; Sprengel, R.; Korpi, E. R.: Attenuation of novelty-induced hyperactivity of gria1-/- mice by cannabidiol and hippocampal inhibitory chemogenetics. Frontiers in pharmacology, 309, S. 1 - 11 (2019)

Reinert, J. K.; Sonntag, I.; Sonntag, H.; Sprengel, R.; Pelzer, P.; Lessle, S.; Kaiser, M.; Kuner, T.: retroLEAP: rAAV-based retrograde trans-synaptic labeling, expression and perturbation. bioRXiv, S. 1 - 13 (2019)

Heuser, K.; Nome, C. G.; Pettersen, K. H.; Åbjørsbråten, K. S.; Jensen, V.; Tang, W.; Sprengel, R.; Taubøll, E.; Nagelhus, E. A.; Enger, R.: Ca2+ signals in astrocytes facilitate spread of epileptiform activity. Cerebral Cortex 28 (11), S. 4036 - 4048 (2018)

Berkel, S.; Eltokhi, A.; Fröhlich, H.; Porras-Gonzalez, D.; Rafiullah, R.; Sprengel, R.; Rappold, G. A.: Sex hormones regulate SHANK expression. Frontiers in Molecular Neuroscience 2018 (11), 337, S. 1 - 10 (2018)

Ang, G.; McKillop, L. E.; Purple, R.; Blanco-Duque, C.; Peirson, S. N.; Foster, R. G.; Harrison, P. J.; Sprengel, R.; Davies, K. E.; Oliver, P. L. et al.; Bannerman, D. M.; Vyazovskiy, V. V.: Absent sleep EEG spindle activity in GluA1 (Gria1) knockout mice: relevance to neuropsychiatric disorders. Translational Psychiatry 8 (1), 154, S. 1 - 14 (2018)

Eltokhi, A.; Rappold , G.; Sprengel, R.: Distinct Phenotypes of shank2 mouse models reflect neuropsychiatric spectrum disorders of human patients with SHANK2 variants. Frontiers in Molecular Neuroscience 2018 (11), 240, S. 1 - 15 (2018)

Bannerman, D. M.; Borchardt, T.; Jensen, V.; Rozov, A.; Haj-Yasein, N. N.; Burnashev, N.; Zamanillo, D.; Bus, T.; Grube, I.; Adelmann, G. et al.; Rawlins, J. N. P.; Sprengel, R.: Somatic accumulation of GluA1-AMPA receptors leads to selective cognitive impairments in mice. Frontiers in Molecular Neuroscience 2018 (11), 199, S. 1 - 14 (2018)

Lang, E.; Mallien, A. S.; Vasilescu, A.-N.; Hefter, D.; Luoni, A.; Riva, M. A.; Borgwardt, S.; Sprengel, R.; Lang, U. E.; Gass, P. et al.; Inta, D.: Molecular and cellular dissection of NMDA receptor subtypes as antidepressant targets. Neuroscience and Biobehavioral Reviews 84, S. 352 - 358 (2018)