Publikationen von Michael Koenen

Semino, F.; Darche, F. F.; Bruehl, C.; Koenen, M.; Skladny, H.; Katus, H. A.; Frey, N.; Draguhn, A.; Schweizer, P. A.: GPD1L-A306del modifies sodium current in a family carrying the dysfunctional SCN5A-G1661R mutation associated with Brugada syndrome. Pflügers Archiv: European Journal of Physiology 476 (2), S. 229 - 242 (2024)

Darche, F. F.; Ullrich, N. D.; Huang, Z.; Koenen, M.; Rivinius, R.; Frey, N.; Schweizer, P. A.: Improved generation of human induced pluripotent stem cell-derived cardiac pacemaker cells using novel differentiation protocols. International Journal of Molecular Sciences 23 (13), 7318, S. 1 - 19 (2022)

Darche, F. F.; Rivinius, R.; Rahm, A.-K.; Köllensperger, E.; Leimer, U.; Germann, G.; Reiss, M.; Koenen, M.; Katus, H. A.; Thomas, D. et al.; Schweizer, P. A.: In vivo cardiac pacemaker function of differentiated human mesenchymal stem cells from adipose tissue transplanted into porcine hearts. World Journal of Stem Cells 12 (10), 55683, S. 1133 - 1151 (2020)

Malik, R.; Darche, F. F.; Rivinius, R.; Seckinger, A.; Krause, U.; Koenen, M.; Thomas, D.; Katus, H. A.; Schweizer, P. A.: Quantitative efficacy and fate of mesenchymal stromal cells targeted to cardiac sites by radiofrequency catheter ablation. Cell Transplantation 29, 963689720914236, S. 1 - 12 (2020)

Weigl, I.; Geschwill, P.; Reiss, M.; Bruehl, C.; Draguhn, A.; Koenen, M.; Sedaghat-Hamedani, F.; Meder, B.; Thomas, D.; Katus, H. A. et al.; Schweizer, P. A.: The C-terminal HCN4 variant P883R alters channel properties and acts as genetic modifier of atrial fibrillation and structural heart disease. Biochemical and Biophysical Research Communications 519 (1), S. 141 - 147 (2019)

Darche, F. F.; Rivinius, R.; Köllensperger, E.; Leimer, U.; Germann, G.; Seckinger, A.; Hose, D.; Schröter, J.; Bruehl, C.; Draguhn, A. et al.; Gabriel, R.; Schmidt, M.; Koenen, M.; Thomas, D.; Katus, H. A.; Schweizer, P. A.: Pacemaker cell characteristics of differentiated and HCN4-transduced human mesenchymal stem cells. Life Sciences 232 (116620), S. 1 - 16 (2019)

Yampolsky, P.; Koenen, M.; Mosqueira, M.; Geschwill, P.; Nauck, S.; Witzenberger, M.; Seyler, C.; Fink, T.; Kruska, M.; Bruehl, C. et al.; Schwoerer, A. P.; Ehmke, H.; Fink, R. H. A.; Draguhn, A.; Thomas, D.; Katus, H. A.; Schweizer, P. A.: Augmentation of myocardial If dysregulates calcium homeostasis and causes adverse cardiac remodeling. Nature Communications 10 (1), 3295, S. 1 - 16 (2019)

Gessnera, G.; Runge, S.; Koenen, M.; Heinemann, S. H.; Koenen, M.; Haas, J.; Meder, B.; Thomas, D.; Katus, H. A.; Schweizer, P. A.: ANK2 functionally interacts with KCNH2 aggravating long QT syndrome in a double mutation carrier. Biochemical and Biophysical Research Communications 512 (4), S. 845 - 851 (2019)

Schweizer, P. A.; Darche, F. F.; Ullrich, N. D.; Geschwill, P.; Greber, B.; Rivinius, R.; Seyler, C.; Müller-Decker, K.; Draguhn, A.; Utikal, J. et al.; Koenen, M.; Katus, H. A.; Thomas, D.: Subtype-specific differentiation of cardiac pacemaker cell clusters from human induced pluripotent stem cells. Stem Cell Research 8, 229, S. 1 - 15 (2017)

Schweizer, P. A.; Schröter, J.; Greiner, S.; Haas, J.; Yampolsky, P.; Mereles, D.; Buss, S. J.; Seyler, C.; Bruehl, C.; Draguhn, A. et al.; Koenen, M.; Meder, B.; Katus, H. A.; Thomas, D.: The symptom complex of familial sinus node dysfunction and myocardial noncompaction is associated with mutations in the HCN4 channel. Journal of the American College of Cardiology 64 (8), S. 757 - 767 (2014)

Rutschow, D.; Bauer, R.; Göhringer, C.; Bekeredjian, R.; Schinkel, S.; Straub, V.; Koenen, M.; Weichenhan, D.; Katus, H. A.; Müller, O. J.: S151A δ-sarcoglycan mutation causes a mild phenotype of cardiomyopathy in mice. European journal of human genetics 22 (1), S. 119 - 125 (2014)

Duhme, N.; Schweizer, P.; Thomas, D.; Becker, R.; Schröter, J.; Barends, T.; Schlichting, I.; Draguhn, A.; Bruehl, C.; Katus, H. A. et al.; Koenen, M.: Altered HCN4 channel C-linker interaction is associated with familial tachycardia–bradycardia syndrome and atrial fibrillation. European Heart Journal 34 (35), S. 2768 - 2775 (2013)

Soucek, R.; Thomas, D.; Kelemen, K.; Bikou, O.; Seyler, C.; Voss, F.; Becker, R.; Koenen, M.; Katus, H. A.; Bauer, A.: Genetic suppression of atrial fibrillation using a dominant-negative ether-a-go-go-related gene mutant. Heart Rhythm 9 (2), S. 265 - 272 (2012)

Pacifici, P. G.; Peter, C.; Yampolsky, P.; Koenen, M.; McArdle, J. J.; Witzemann, V.: Novel mouse model reveals distinct activity-dependent and -independent contributions to synapse development. PLoS One 6 (1), e16469, S. 1 - 13 (2011)

Schweizer, P. A.; Duhme, N.; Thomas, D.; Becker, R.; Zehelein, J.; Draguhn, A.; Bruehl, C.; Katus, H. A.; Koenen, M.: cAMP sensitivity of HCN pacemaker channels determines basal heart rate but is not critical for autonomic rate control. Circulation: Arrhythmia and Electrophysiology 3 (5), S. 542 - 552 (2010)

Thomas, D.; Khalil, M.; Alter, M.; Schweizer, P.; Karle, C. A.; Wimmer, A.-B.; Licka, M.; Katus, H. A.; Koenen, M.; Ulmer, H. E. et al.; Zehelein, J.: Biophysical characterization of KCNQ1 P320 mutations linked to long QT syndrome 1. Journal of Molecular and Cellular Cardiology (London) 48 (1), S. 230 - 237 (2010)

Schweizer, P.; Yampolsky, P.; Malik, R.; Thomas, D.; Zehelein, J.; Katus, H. A.; Koenen, M.: Transcription profiling of HCN-channel isotypes throughout mouse cardiac development. Basic Research in Cardiology 104 (6), S. 621 - 629 (2009)

Opherk, J.-P.; Yampolsky, P.; Hardt, S. E.; Schoels, W.; Katus, H. A.; Koenen, M.; Zehelein, J.: Cardiac-specific activation of Cre expression at late fetal development. Biochemical and Biophysical Research Communications 359 (2), S. 209 - 213 (2007)

Schweizer, P. A.; Krause, U.; Becker, R.; Seckinger, A.; Bauer, A.; Hardt, C.; Eckstein, V.; Ho, A. D.; Koenen, M.; Katus, H. A. et al.; Zehelein, J.: Atrial-radiofrequency catheter ablation mediated targeting of mesenchymal stromal cells. Stem Cells 25 (6), S. 1546 - 1551 (2007)

Zehelein, J.; Kathöfer, S.; Khalil, M.; Alter, M.; Thomas, D.; Brockmeier, K.; Ulmer, H. E.; Katus, H. A.; Koenen, M.: Skipping of exon 1 in the KCNQ1 gene causes Jervell and Lange-Nielsen syndrome. The Journal of Biological Chemistry 281 (46), S. 35397 - 35403 (2006)