Publications of Rolf Sprengel

Higuchi, M.; Maas, S.; Single, F. N.; Hartner, J. C.; Rozov, A.; Burnashev, N.; Feldmeyer, D.; Sprengel, R.; Seeburg, P. H.: Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2. Nature 406 (6791), pp. 78 - 81 (2000)

Single, F. N.; Rozov, A.; Burnashev, N.; Zimmermann, F.; Hanley, D. F.; Forrest, D.; Curran, T.; Jensen, V.; Hvalby, Ø.; Sprengel, R. et al.; Seeburg, P. H.: Dysfunction in mice by NMDA receptor point mutations NR1(N598Q) and NR1(N598R). The Journal of Neuroscience: the Official Journal of the Society for Neuroscience 20 (7), pp. 2558 - 2566 (2000)

Zamanillo, D.; Sprengel, R.; Hvalby, Ø.; Jensen, V.; Burnashev, N.; Rozov, A.; Kaiser, K.; Köster, H. J.; Borchardt, T.; Worley, P. F. et al.; Lübke, J. H. R.; Frotscher, M.; Kelly, P. H.; Sommer, B.; Andersen, P.; Seeburg, P. H.; Sakmann, B.: Importance of AMPA receptors for hippocampal synaptic plasticity but not for spatial learning. Science 284, pp. 1805 - 1811 (1999)

Jerecic, J.; Single, F. N.; Krüth, U.; Krestel, H. E.; Kolhekar, R.; Storck, T.; Kask, K.; Higuchi, M.; Sprengel, R.; Seeburg, P. H.: Studies on conditional gene expression in the brain. Annals of the New York Academy of Sciences 868, pp. 27 - 37 (1999)

Sprengel, R.; Single, F. N.: Mice with genetically modified NMDA and AMPA receptors. Annals of the New York Academy of Sciences 868, pp. 494 - 501 (1999)

Spergel, D. J.; Krüth, U.; Hanley, D. F.; Sprengel, R.; Seeburg, P. H.: GABA- and glutamate-activated channels in green fluorescent protein-tagged gonadotropin-releasing hormone neurons in transgenic mice. The Journal of Neuroscience 19 (6), pp. 2037 - 2050 (1999)

Feldmeyer, D.; Kask, K.; Brusa, R.; Kornau, H. C.; Kolhekar, R.; Rozov, A.; Burnashev, N.; Jensen, V.; Hvalby, Ø.; Sprengel, R. et al.; Seeburg, P. H.: Neurological dysfunctions in mice expressing different levels of the Q/R site-unedited AMPAR subunit GluR-B. Nature Neuroscience 2 (2), pp. 57 - 64 (1999)

Kask, K.; Zamanillo, D.; Rozov, A.; Burnashev, N.; Sprengel, R.; Seeburg, P. H.: The AMPA receptor subunit GluR-B in its Q/R site-unedited form is not essential for brain development and function. Proceedings of the National Academy of Sciences of the United States of America 95 (23), pp. 13777 - 13782 (1998)

Seeburg, P. H.; Higuchi, M.; Sprengel, R.: RNA editing of brain glutamate receptor channels: mechanism and physiology. Brain Research Reviews 26 (2-3), pp. 217 - 229 (1998)

Eskola, V.; Ryhänen, P.; Savisalo, M.; Rannikko, A.; Kananen, K.; Sprengel, R.; Huhtaniemi, I. T.: Stable transfection of the rat follicle-stimulating hormone receptor complementary DNA into an immortalized murine Sertoli cell line. Molecular and Cellular Endocrinology 139 (1-2), pp. 143 - 152 (1998)

Sprengel, R.; Suchanek, B.; Amico, C.; Brusa, R.; Burnashev, N.; Rozov, A.; Hvalby, Ø.; Jensen, V.; Paulsen, O.; Andersen, P. et al.; Kim, J. J.; Thompson, R. F.; Sun, W.; Webster, L. C.; Grant, S. G. N.; Eilers, J.; Konnerth, A.; McNamara, J. O.; Seeburg, P. H.: Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo. Cell 92, pp. 279 - 289 (1998)

Seeburg, P. H.; Brusa, R.; Higuchi, M.; Sprengel, R.: Glutamate receptor channels, RNA editing, and epilepsy. Ernst Schering Research Foundation workshop 23 (1), pp. 1 - 17 (1998)

Suchanek, B.; Seeburg, P. H.; Sprengel, R.: Tissue specific control regions of the N-methyl-D-aspartate receptor subunit NR2C promotorsubunit NR2C promotor. Biological Chemistry 378, pp. 929 - 934 (1997)

Melcher, T.; Maas, S.; Herb, A.; Sprengel, R.; Higuchi, M.; Seeburg, P. H.: RED2, a brain specific member of the RNA specific adenosine deaminase family. The Journal of Biological Chemistry 271 (50), pp. 31795 - 31798 (1996)

Storck, T.; Storck, U.; Kolhekar, R.; Sprengel, R.; Seeburg, P. H.: Rapid construction in yeast of complex targeting vectors for gene manipulation in the mouse. Nucleic Acids Research (London) 24 (22), pp. 4594 - 4596 (1996)

Herb, A.; Higuchi, M.; Sprengel, R.; Seeburg, P. H.: Q/R site editing in kainate receptor GluR5 and GluR6 pre-mRNAs requires distant intronic sequences. Proceedings of the National Academy of Sciences of the United States of America 93 (5), pp. 1875 - 1880 (1996)

Melcher, T.; Maas, S.; Herb, A.; Sprengel, R.; Seeburg, P. H.; Higuchi, M.: A mammalian RNA editing enzyme. Nature 379, pp. 460 - 464 (1996)

Brusa, R.; Zimmermann, F.; Koh, D. S.; Feldmeyer, D.; Gass, P.; Seeburg, P. H.; Sprengel, R.: Early-onset epilepsy and postnatal lethality associated with an editing-deficient GluR-B allele in mice. Science 270 (5242), pp. 1677 - 1680 (1995)

Suchanek, B.; Seeburg, P. H.; Sprengel, R.: Gene Structure of the Murine N-Methyl D-Aspartate Receptor Subunit NR2C. The Journal of Biological Chemistry 270 (1), pp. 41 - 44 (1995)

Seeburg, P. H.; Burnashev, N.; Köhr, G.; Kuner, T.; Sprengel, R.; Monyer, H.: The NMDA receptor channel: molecular design of a coincidence detector. Recent Prog. Horm. Res. 50, pp. 19 - 34 (1995)