There is an urgent need to be able to synthesize modified glycopeptide antibiotics quickly to keep up with the problem of bacterial resistance. On an industrial scale this is currently not possible, because the crucial steps of the natural antibiotic synthesis are too little understood. New detailed insights into these mechanisms offer the hope of simulating this process in the laboratory, to allow a variety of more substantially altered glycopeptide antibiotics to be produced in rapid response to developing bacterial resistance.
Perception of visual motion is of fundamental importance in order to safely move around and to skillfully reach and grasp objects. When using visual input to control goal-directed motion, our brain makes a decision to select the object of greatest salience in the visual field in order to steer the eyes, the head and the hand towards it. Even the small zebrafish larva exhibits a complex goal-directed behavior thanks to its refined visual system. Research at the Max Planck Institute for Medical Research now reveals how motion stimuli are processed in the brain of this little hunter.