Publications of J Reinstein

Goody, R.; Reinstein, J.; Scheidig, A.; Schlichting, I.: Die vierte Dimension in der molekularen Strukturforschung. Dortmunder UNI Report 1990 (Sonderheft), pp. 40 - 45 (1999)

Gruen, M.; Becker, C.; Beste, A.; Reinstein, J.; Scheidig, A. J.; Goody, R. S.: 2′Halo-ATP and -GTP analogues: Rational phasing tools for protein crystallography. Protein Science 8 (11), pp. 2524 - 2528 (1999)

Lavie, A.; Ostermann, N.; Brundiers, R.; Goody, R. S.; Reinstein, J.; Konrad, M.; Schlichting, I.: Structural basis for efficient phosphorylation of 3'-azidothymidine monophosphate by Escherichia coli thymidylate kinase. Proceedings of the National Academy of Sciences of the United States of America 95 (24), pp. 14045 - 14050 (1998)

Klostermeier, D.; Seidel, R.; Reinstein, J.: Functional properties of the molecular chaperone DnaK from Thermus thermophilus. Journal of Molecular Biology (London) 279 (4), pp. 841 - 853 (1998)

Lavie, A.; Konrad, M.; Brundiers, R.; Goody, R. S.; Schlichting, I.; Reinstein, J.: Crystal structure of yeast thymidylate kinase complexed with the bisubstrate inhibitor P1-(5'-adenosyl) P5-(5'-thymidyl) pentaphosphate (TP5A) at 2.0 A resolution: implications for catalysis and AZT activation. Biochemistry 37 (11), pp. 3677 - 3686 (1998)

Lavie, A.; Reinstein, J.; Goody, R. S.; Schlichting, I.; Konrad, M.: Reply to "Improving AZT efficacy". Nature Medicine 4, p. 132 - 132 (1998)

Lavie, A.; Reinstein, J.; Goody, R. S.; Schlichting, I.; Konrad, M.: Improving AZT efficacy. Nature Medicine 4 (2), p. 132 - 132 (1998)

Schlichting, I.; Reinstein, J.: Structure of active conformations of UMP kinase from Dictyostelium discoideum suggest phosphoryl transfer is associative. Biochemistry 36, pp. 9290 - 9296 (1997)

Schlichting, I.; Reinstein, J.: Structures of active conformations of UMP kinase from Dictyostelium discoideum suggest phosphoryl transfer is associative. Biochemistry 36 (31), pp. 9290 - 9296 (1997)

Lavie, A.; Schlichting, I.; Vetter, I. R.; Konrad, M.; Reinstein, J.; Goody, R. S.: The bottleneck in AZT activation. Nature Medicine 3 (8), pp. 922 - 924 (1997)

Lavie, A.; Vetter, I. R.; Konrad, M.; Goody, R. S.; Reinstein, J.; Schlichting, I.: Structure of thymidylate kinase reveals the cause behind the limiting step in AZT activation. Nature structural biology 4 (8), pp. 601 - 604 (1997)

Scheibel, T.; Neuhofen, S.; Weikl, T.; Mayr, C.; Reinstein, J.; Vogel, P. D.; Buchner, J.: ATP-binding properties of human Hsp90. The Journal of Biological Chemistry 272 (30), pp. 18608 - 18613 (1997)

Packschies, L.; Theyssen, H.; Buchberger, A.; Bukau, B.; Goody, R. S.; Reinstein, J.: GrpE accelerates nucleotide exchange of the molecular chaperone DnaK with an associative displacement mechanism. Biochemistry 36 (12), pp. 3417 - 3422 (1997)

Theyssen, H.; Schuster, H.-P.; Packschies, L.; Bukau, B.; Reinstein, J.: The second step of ATP binding to DnaK induces peptide release. Journal of Molecular Biology (London) 263 (5), pp. 657 - 670 (1996)

Neuhofen, S.; Theyssen, H.; Reinstein, J.; Trommer, W. E.; Vogel, P. D.: Nucleotide binding to the heat-shock protein DnaK as studied by ESR spectroscopy. European Journal of Biochemistry 240 (1), pp. 78 - 82 (1996)

Scheffzek, K.; Kliche, W.; Wiesmüller, L.; Reinstein, J.: Crystal structure of the complex of UMP/CMP kinase from Dictyostelium discoideum and the bisubstrate inhibitor P1-(5'-Adenosyl)-P5- (5'-Uridyl) Pentaphosphate (UP5A ) and Mg2+ at 2.2 Å: implications for water-mediated specificity. Biochemistry 35 (30), pp. 9716 - 9727 (1996)

Jakob, U.; Scheibel, T.; Bose, S.; Reinstein, J.; Buchner, J.: Assessment of the ATP binding properties of Hsp90. The Journal of Biological Chemistry 271 (17), pp. 10035 - 10041 (1996)

Thrall, S. H.; Reinstein, J.; Wöhrl, B. M.; Goody, R. S.: Evaluation of human immunodeficiency virus type 1 reverse transcriptase primer tRNA binding by fluorescence spectroscopy: specificity and comparison to primer/template binding. Biochemistry 35 (14), pp. 4609 - 4618 (1996)

Müller, C. W.; Schlauderer, G. J.; Reinstein, J.; Schulz, G. E.: Adenylate kinase motions during catalysis: an energetic counterweight balancing substrate binding. Structure 4 (2), pp. 147 - 156 (1996)

Vogel, P. D.; Neuhofen, S.; Theyssen, H.; Reinstein, J.; Trommer, W. E.: Investigating nucleotide-binding to the heat-shock protein dnak using esr-spectroscopy. Biophysical Journal 70, pp. 433 - 321 (1996)