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Journal Article (48)

  1. 1.
    Journal Article
    Weigl, I.; Geschwill, P.; Reiss, M.; Bruehl, C.; Draguhn, A.; Koenen, M.; Sedaghat-Hamedani, F.; Meder, B.; Thomas, D.; Katus, H. A. et al.; Schweizer, P. A.: The C-terminal HCN4 variant P883R alters channel properties and acts as genetic modifier of atrial fibrillation and structural heart disease. Biochemical and Biophysical Research Communications 519 (1), pp. 141 - 147 (2019)
  2. 2.
    Journal Article
    Darche, F. F.; Rivinius, R.; Köllensperger, E.; Leimer, U.; Germann, G.; Seckinger, A.; Hose, D.; Schröter, J.; Bruehl, C.; Draguhn, A. et al.; Gabriel, R.; Schmidt, M.; Koenen, M.; Thomas, D.; Katus, H. A.; Schweizer, P. A.: Pacemaker cell characteristics of differentiated and HCN4-transduced human mesenchymal stem cells. Life Sciences 232 (116620), e-pup, pp. 1 - 16 (2019)
  3. 3.
    Journal Article
    Yampolsky, P.; Koenen, M.; Mosqueira, M.; Geschwill, P.; Nauck, S.; Witzenberger, M.; Seyler, C.; Fink, T.; Kruska, M.; Bruehl, C. et al.; Schwoerer, A. P.; Ehmke, H.; Fink, R. H. A.; Draguhn, A.; Thomas, D.; Katus, H. A.; Schweizer, P. A.: Augmentation of myocardial If dysregulates calcium homeostasis and causes adverse cardiac remodeling. Nature Communications 10 (1), 3295, pp. 1 - 16 (2019)
  4. 4.
    Journal Article
    Gessnera, G.; Runge, S.; Koenen, M.; Heinemann, S. H.; Koenen, M.; Haas, J.; Meder, B.; Thomas, D.; Katus, H. A.; Schweizer, P. A.: ANK2 functionally interacts with KCNH2 aggravating long QT syndrome in a double mutation carrier. Biochemical and Biophysical Research Communications 512 (4), pp. 845 - 851 (2019)
  5. 5.
    Journal Article
    Schweizer, P. A.; Darche, F. F.; Ullrich, N. D.; Geschwill, P.; Greber, B.; Rivinius, R.; Seyler, C.; Müller-Decker, K.; Draguhn, A.; Utikal, J. et al.; Koenen, M.; Katus, H. A.; Thomas, D.: Subtype-specific differentiation of cardiac pacemaker cell clusters from human induced pluripotent stem cells. Stem Cell Research 8 (229) (2017)
  6. 6.
    Journal Article
    Schweizer, P. A.; Schröter, J.; Greiner, S.; Haas, J.; Yampolsky, P.; Mereles, D.; Buss, S. J.; Seyler, C.; Bruehl, C.; Draguhn, A. et al.; Koenen, M.; Meder, B.; Katus, H. A.; Thomas, D.: The symptom complex of familial sinus node dysfunction and myocardial noncompaction is associated with mutations in the HCN4 channel. Journal of the American College of Cardiology 64 (8), pp. 757 - 767 (2014)
  7. 7.
    Journal Article
    Rutschow, D.; Bauer, R.; Göhringer, C.; Bekeredjian, R.; Schinkel, S.; Straub, V.; Koenen, M.; Weichenhan, D.; Katus, H. A.; Müller, O. J.: S151A δ-sarcoglycan mutation causes a mild phenotype of cardiomyopathy in mice. European journal of human genetics 22 (1), pp. 119 - 125 (2014)
  8. 8.
    Journal Article
    Duhme, N.; Schweizer, P.; Thomas, D.; Becker, R.; Schröter, J.; Barends, T.; Schlichting, I.; Draguhn, A.; Bruehl, C.; Katus, H. A. et al.; Koenen, M.: Altered HCN4 channel C-linker interaction is associated with familial tachycardia–bradycardia syndrome and atrial fibrillation. European Heart Journal 34 (35), pp. 2768 - 2775 (2013)
  9. 9.
    Journal Article
    Soucek, R.; Thomas, D.; Kelemen, K.; Bikou, O.; Seyler, C.; Voss, F.; Becker, R.; Koenen, M.; Katus, H. A.; Bauer, A.: Genetic suppression of atrial fibrillation using a dominant-negative ether-a-go-go-related gene mutant. Heart Rhythm 9 (2), pp. 265 - 272 (2012)
  10. 10.
    Journal Article
    Pacifici, P. G.; Peter, C.; Yampolsky, P.; Koenen, M.; McArdle, J. J.; Witzemann, V.: Novel mouse model reveals distinct activity-dependent and -independent contributions to synapse development. PLoS One 6 (1), e16469, pp. 1 - 13 (2011)
  11. 11.
    Journal Article
    Schweizer, P. A.; Duhme, N.; Thomas, D.; Becker, R.; Zehelein, J.; Draguhn, A.; Bruehl, C.; Katus, H. A.; Koenen, M.: cAMP sensitivity of HCN pacemaker channels determines basal heart rate but is not critical for autonomic rate control. Circulation: Arrhythmia and Electrophysiology 3 (5), pp. 542 - 552 (2010)
  12. 12.
    Journal Article
    Thomas, D.; Khalil, M.; Alter, M.; Schweizer, P.; Karle, C. A.; Wimmer, A.-B.; Licka, M.; Katus, H. A.; Koenen, M.; Ulmer, H. E. et al.; Zehelein, J.: Biophysical characterization of KCNQ1 P320 mutations linked to long QT syndrome 1. Journal of Molecular and Cellular Cardiology (London) 48 (1), pp. 230 - 237 (2010)
  13. 13.
    Journal Article
    Schweizer, P.; Yampolsky, P.; Malik, R.; Thomas, D.; Zehelein, J.; Katus, H. A.; Koenen, M.: Transcription profiling of HCN-channel isotypes throughout mouse cardiac development. Basic Research in Cardiology 104 (6), pp. 621 - 629 (2009)
  14. 14.
    Journal Article
    Opherk, J.-P.; Yampolsky, P.; Hardt, S. E.; Schoels, W.; Katus, H. A.; Koenen, M.; Zehelein, J.: Cardiac-specific activation of Cre expression at late fetal development. Biochemical and Biophysical Research Communications 359 (2), pp. 209 - 213 (2007)
  15. 15.
    Journal Article
    Schweizer, P. A.; Krause, U.; Becker, R.; Seckinger, A.; Bauer, A.; Hardt, C.; Eckstein, V.; Ho, A. D.; Koenen, M.; Katus, H. A. et al.; Zehelein, J.: Atrial-radiofrequency catheter ablation mediated targeting of mesenchymal stromal cells. Stem Cells 25 (6), pp. 1546 - 1551 (2007)
  16. 16.
    Journal Article
    Zehelein, J.; Kathöfer, S.; Khalil, M.; Alter, M.; Thomas, D.; Brockmeier, K.; Ulmer, H. E.; Katus, H. A.; Koenen, M.: Skipping of exon 1 in the KCNQ1 gene causes Jervell and Lange-Nielsen syndrome. The Journal of Biological Chemistry 281 (46), pp. 35397 - 35403 (2006)
  17. 17.
    Journal Article
    Thomas, D.; Wimmer, A.-B.; Karle, C. A.; Licka, M.; Alter, M.; Khalil, M.; Ulmer, H. E.; Kathöfer, S.; Kiehn, J.; Katus, H. A. et al.; Schoels, W.; Koenen, M.; Zehelein, J.: Dominant-negative I(Ks) suppression by KCNQ1-deltaF339 potassium channels linked to Romano-Ward syndrome. Cardiovascular Research 67 (3), pp. 487 - 497 (2005)
  18. 18.
    Journal Article
    Koenen, M.; Peter, C.; Villarroel, A.; Witzemann, V.; Sakmann, B.: Acetylcholine receptor channel subtype directs the innervation pattern of skeletal muscle. EMBO Reports 6 (6), pp. 570 - 576 (2005)
  19. 19.
    Journal Article
    Zehelein, J.; Thomas, D.; Khalil, M.; Wimmer, A.-B.; Koenen, M.; Licka, M.; Wu, K.; Kiehn, J.; Brockmeier, K.; Kreye, V. A. et al.; Karle, C. A.; Katus, H. A.; Ulmer, H. E.; Schoels, W.: Identification and characterisation of a novel KCNQ1 mutation in a family with Romano-Ward syndrome. Biochimica et Biophysica Acta 1690 (3), pp. 185 - 192 (2004)
  20. 20.
    Journal Article
    Chun, J.; Koenen, M.; Katus, H. A.; Zehelein, J.: Expression of the IKr components KCNH2 (rERG) and KCNE2 (rMiRP1) during late rat heart development. Experimental & molecular medicine 36 (4), pp. 367 - 371 (2004)
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