Publications of Matthias Geyer

Stumber, M.; Geyer, M.; Graf, R.; Kalbitzer, H. R.; Scheffzek, K.; Haeberlen, U.: Observation of slow dynamic exchange processes in Ras protein crystals by ³¹P solid state NMR spectroscopy. Journal of Molecular Biology (London) 323 (5), pp. 899 - 907 (2002)

Nekrep, N.; Jabrane-Ferrat, N.; Wolf, H. M.; Eibl, M. M.; Geyer, M.; Peterlin, M.: Mutation in a winged-helix DNA-binding motif causes atypical bare lymphocyte syndrome. Nature Immunology 3 (11), pp. 1075 - 1081 (2002)

Steiner, G.; Kremer, W.; Linnemann, T.; Herrmann, C.; Geyer, M.; Kalbitzer, H. R.: Sequence-specific resonance assignment of the Ras-binding domain of AF6. Journal of Biomolecular NMR 18 (1), 275267, pp. 73 - 74 (2000)

Praefcke, G. J. K.; Geyer, M.; Schwemmle, M.; Kalbitzer, H. R.; Herrmann, C.: Nucleotide-binding characteristics of human guanylate-binding protein 1 (hGBP1) and identification of the third GTP-binding motif. Journal of Molecular Biology (London) 292 (2), pp. 321 - 332 (1999)

Geyer, M.; Assheuer, R.; Klebe, C.; Kuhlmann, J.; Becker, J.; Wittinghofer, A.; Kalbitzer, H. R.: Conformational states of the nuclear GTP-binding protein Ran and its complexes with the exchange factor RCC1 and the effector protein RanBP1. Biochemistry 38 (35), pp. 11250 - 11260 (1999)

Geyer, M.; Munte, C. E.; Schorr, J.; Kellner, R.; Kalbitzer, H. R.: Structure of the anchor-domain of myristoylated and non-myristoylated HIV-1 Nef protein. Journal of Molecular Biology (London) 289 (1), pp. 123 - 138 (1999)

Vetter, I. R.; Linnemann, T.; Wohlgemuth, S.; Geyer, M.; Kalbitzer, H. R.; Herrmann, C.; Wittinghofer, A.: Structural and biochemical analysis on Ras-effector signaling via RalGDS. FEBS Letters 451 (2), pp. 175 - 180 (1999)

Linnemann, T.; Geyer, M.; Jaitner, B. K.; Block, C.; Kalbitzer, H. R.; Wittinghofer, A.; Herrmann, C.: Thermodynamic and kinetic characterization of the interaction between the Ras binding domain of AF6 and members of the Ras subfamily. The Journal of Biological Chemistry 274 (19), pp. 13556 - 13562 (1999)

Geyer, M.; Wittinghofer, A.: GEFs, GAPs, GDIs and effectors: taking a closer (3D) look at the regulation of Ras-related GTP-binding proteins. Current Opinion in Structural Biology 7 (6), pp. 786 - 792 (1997)

Geyer, M.; Herrmann, C.; Wohlgemuth, S.; Wittinghofer, A.; Kalbitzer, H. R.: Structure of the Ras-binding domain of RalGEF and implications for Ras binding and signalling. Nature structural biology 4 (9), pp. 694 - 699 (1997)

Antz, C.; Geyer, M.; Fakler, B.; Schott, M. K.; Guy, H. R.; Frank, R.; Ruppersberg, J. P.; Kalbitzer, H. R.: NMR structure of inactivation gates from mammalian voltage-dependent potassium channels. Nature 385 (6613), pp. 272 - 275 (1997)

Schweins, T.; Geyer, M.; Kalbitzer, H. R.; Wittinghofer, A.; Warshel, A.: Linear free energy relationships in the intrinsic and GTPase activating protein-stimulated guanosine 5'-triphosphate hydrolysis of p21ras. Biochemistry 35 (45), pp. 14225 - 14231 (1996)

Raditsch, M.; Geyer, M.; Kalbitzer, H. R.; Ruppersberg, J. P.; Jahn, W.; Witzemann, V.: Polyamine spider toxins and NMDA receptors: structural basis for channel block and binding of argiotoxin636. European Journal of Biochemistry 240, pp. 416 - 426 (1996)

Geyer, M.; Schweins, T.; Herrmann, C.; Prisner, T.; Wittinghofer, A.; Kalbitzer, H. R.: Conformational transitions in p21ras and in its complexes with the effector protein Raf-RBD and the GTPase activating protein GAP. Biochemistry 35 (32), pp. 10308 - 10320 (1996)

Neidig, K.-P.; Geyer, M.; Görler, A.; Antz, C.; Saffrich, R.; Beneicke, W.; Kalbitzer, H. R.: AURELIA, a program for computer-aided analysis of multidimensional NMR spectra. Journal of Biomolecular NMR 6 (3), pp. 255 - 270 (1995)

Geyer, M.; Neidig, K.-P.; Kalbitzer, H. R.: Automated peak integration in multidimensional NMR spectra by an optimized iterative segmentation procedure. Journal of Magnetic Resonance Series B 109 (1), pp. 31 - 38 (1995)

Schweins, T.; Geyer, M.; Scheffzek, K.; Warshel, A.; Kalbitzer, H. R.; Wittinghofer, A.: Substrate-assisted catalysis as a mechanism for GTP hydrolysis of p21ras and other GTP-binding proteins. Nature Structural and Molecular Biology 2 (1), pp. 36 - 44 (1995)

Franken, S. M.; Scheidig, A. J.; Krengel, U.; Rensland, H.; Lautwein, A.; Geyer, M.; Scheffzek, K.; Goody, R. S.; Kalbitzer, H. R.; Pai, E. F. et al.; Wittinghofer, A.: Three-dimensional structures and properties of a transforming and a nontransforming glycine-12 mutant of p21H-ras. Biochemistry 32 (33), pp. 8411 - 8420 (1993)

Geyer, M.; Schlichting, I.: Information contained in protein structures determined by NMR in solution or by X-ray Ddiffraction in crystals. In: Simplicity and Complexity in Proteins and Nucleic Acids, pp. 59 - 73 (Eds. Frauenfelder, H.; Deisenhofer, J.; Wolynes, a. P.G.). Dahlem University Press, Berlin (1999)

Geyer, M.: NMR-Spektroskopie zur Analyse biologischer Reaktionsmechanismen: Austauschexperimente an GTP-bindenden Proteinen und Strukturbestimmung der N-terminalen Domäne des Kaliumkanals RCK4. Dissertation, VII, 155 Bl. pp., Ruprecht-Karls-Universität Heidelberg, Heidelberg (1995)