Publications of Jochen Reinstein

Zeymer, C.; Barends, T.; Werbeck, N. D.; Schlichting, I.; Reinstein, J.: Elements in nucleotide sensing and hydrolysis of the AAA+ disaggregation machine ClpB: a structure-based mechanistic dissection of a molecular motor. Acta Crystallographica. Section D: Biological Crystallography (Copenhagen) 70 (2), pp. 582 - 595 (2014)

Reinstein, J.: Proximity effects on the protein domain level: engineering prolyl isomerases through combinatorial biochemistry. Journal of Molecular Biology (London) 425 (22), pp. 4065 - 4066 (2013)

Beitlich, T.; Lorenz, T.; Reinstein, J.: Folding properties of cytosine monophosphate kinase from E. coli indicate stabilization through an additional insert in the NMP binding domain. PLoS One 8 (10), e78384, pp. 1 - 14 (2013)

Winkler, A.; Heintz, U.; Lindner, R.; Reinstein, J.; Shoeman, R. L.; Schlichting, I.: A ternary AppA–PpsR–DNA complex mediates light regulation of photosynthesis-related gene expression. Nature Structural and Molecular Biology 20 (7), pp. 859 - 867 (2013)

Benz, J.; Reinstein, J.; Meinhart, A.: Structural insights into the effector – immunity system Tae4/Tai4 from Salmonella typhimurium. PLoS One 8 (6), 67362, pp. 1 - 14 (2013)

Eckl, J. M.; Rutz, D. A.; Haslbeck, V.; Zierer, B. K.; Reinstein, J.; Richter, K.: Cdc37 (Cell division dycle 37) restricts Hsp90 (Heat shock protein 90) motility by interaction with N-terminal and middle domain binding sites. Journal of Biological Chemistry 288 (22), pp. 16032 - 16042 (2013)

Zeymer, C.; Werbeck, N. D.; Schlichting, I.; Reinstein, J.: The molecular mechanism of Hsp100 chaperone inhibition by the prion curing agent guanidinium chloride. Journal of Biological Chemistry 288 (10), pp. 7065 - 7076 (2013)

Li, J.; Richter, K.; Reinstein, J.; Buchner, J.: Integration of the accelerator Aha1 in the Hsp90 co-chaperone cycle. Nature Structural and Molecular Biology 20 (3), pp. 326 - 331 (2013)

Barends, T.; Brosi, R. W. W.; Steinmetz, A.; Scherer, A.; Hartmann, E.; Eschenbach, J.; Lorenz, T.; Seidel, R.; Shoeman, R. L.; Zimmermann, S. et al.; Bittl, R.; Schlichting, I.; Reinstein, J.: Combining crystallography and EPR: crystal and solution structures of the multidomain cochaperone DnaJ. Acta Crystallographica. Section D: Biological Crystallography (Copenhagen) 69 (8), pp. 1540 - 1552 (2013)

Schweizer, R.; Reinstein, J.: Protein-Origami für Fortgeschrittene: Wie DnaK besser falten lernte. Biospektrum 18 (4), pp. 372 - 375 (2012)

Schweizer, R.; Aponte, R. A.; Zimmermann, S.; Weber, A.; Reinstein, J.: Fine tuning of a biological machine: DnaK gains improved chaperone activity by altered allosteric communication and substrate binding. ChemBioChem: A European Journal of Chemical Biology 12 (10), pp. 1559 - 1573 (2011)

Werbeck, N. D.; Zeymer, C.; Kellner, J.; Reinstein, J.: Coupling of oligomerization and nucleotide binding in the AAA+ chaperone ClpB. Biochemistry 50 (5), pp. 899 - 909 (2011)

Mutschler, H.; Reinstein, J.; Meinhart, A.: Assembly dynamics and stability of the pneumococcal epsilon zeta antitoxin toxin (PezAT) system from Streptococcus pneumoniae. The Journal of Biological Chemistry 285 (28), pp. 21797 - 21806 (2010)

Aponte, R. A.; Zimmermann, S.; Reinstein, J.: Directed evolution of the DnaK chaperone: mutations in the lid domain result in enhanced chaperone activity. Journal of Molecular Biology (London) 399 (1), pp. 154 - 167 (2010)

Barends, T.; Werbeck, N. D.; Reinstein, J.: Disaggregases in 4 dimensions. Current Opinion in Structural Biology 20 (1), pp. 46 - 53 (2010)

Kuzmic, P.; Lorenz, T.; Reinstein, J.: Analysis of residuals from enzyme kinetic and protein folding experiments in the presence of correlated experimental noise. Analytical Biochemistry 395 (1), pp. 1 - 7 (2009)

Werbeck, N. D.; Kellner, J.; Barends, T.; Reinstein, J.: Nucleotide binding and allosteric modulation of the second AAA+ fomain of ClpB probed by transient kinetic studies. Biochemistry 48 (30), pp. 7240 - 7250 (2009)

Barends, T.; Hartmann, E.; Griese, J.; Beitlich, T.; Kirienko, N. V.; Ryjenkov, D. A.; Reinstein, J.; Shoeman, R. L.; Gomelsky, M.; Schlichting, I.: Structure and mechanism of a bacterial light-regulated cyclic nucleotide phosphodiesterase. Nature 459 (7249), pp. 1015 - 1018 (2009)

Popp, S.; Reinstein, J.: Functional characterization of the DnaK chaperone system from the archaeon Methanothermobacter thermautotrophicus ΔH. FEBS Letters 583 (3), pp. 573 - 578 (2009)

Lorenz, T.; Reinstein, J.: The influence of proline isomerization and off-pathway intermediates on the folding mechanism of eukaryotic UMP/CMP Kinase. Journal of Molecular Biology (London) 381 (2), pp. 443 - 455 (2008)