Publications of Johannes Broichhagen

Journal Article (16)

Journal Article
Kemter, E.; Müller, A.; Neukam, M.; Ivanova, A.; Klymiuk, N.; Renner, S.; Yang, K.; Broichhagen, J.; Kurome, M.; Zakhartchenko, V. et al.; Kessler, B.; Knoch, K.-P.; Bickle, M.; Ludwig, B.; Johnsson, K.; Lickert, H.; Kurth, T.; Wolf, E.; Solimena, M.: Sequential in vivo labeling of insulin secretory granule pools in INS-SNAP transgenic pigs. Proceedings of the National Academy of Sciences of the United States of America 118 (37), e2107665118, pp. 1 - 8 (2021)
Journal Article
Ast, J.; Novak, A. N.; Podewin, T.; Fine, N. H.F.; Jones, B.; Tomas, A.; Birke, R.; Roßmann, K.; Mathes, B.; Eichhorst, J. et al.; Lehmann, M.; Linnemann, A. K.; Hodson, D. J.; Broichhagen, J.: An expanded LUXendin color palette for GLP1R detection and visualization in vitro and in vivo. ChemRxiv, pp. 1 - 23 (2021)
Journal Article
Lämmle, C. A.; Varady, A.; Müller, T. G.; Sturtzel, C.; Riepl, M.; Mathes, B.; Eichhorst, J.; Sporbert, A.; Lehmann, M.; Kräusslich, H.-G. et al.; Distel, M.; Broichhagen, J.: Photocaged hoechst enables subnuclear visualization and cell selective staining of DNA in vivo. ChemBioChem: A European Journal of Chemical Biology 22 (3), pp. 548 - 556 (2021)
Journal Article
Fang, Z.; Chen, S.; Manchanda, Y.; Bitsi, S.; Pickford, P.; David, A.; Shchepinova, M. M.; Corrêa Jr, I. R.; Hodson, D. J.; Broichhagen, J. et al.; Tate, E. W.; Reimann, F.; Salem, V.; Rutter, G. A.; Tan, T.; Bloom, S. R.; Tomas, A.; Jones, B.: Ligand-specific factors influencing GLP-1 receptor post-endocytic trafficking and degradation in pancreatic beta cells. International Journal of Molecular Sciences 21 (21), 8404, pp. 1 - 24 (2020)
Journal Article
Pickford, P.; Lucey, M.; Fang, Z.; Bitsi, S.; de la Serna, J. B.; Broichhagen, J.; Hodson, D. J.; Minnion, J.; Rutter, G. A.; Bloom, S. R. et al.; Tomas, A.; Jones, B.: Signalling, trafficking and glucoregulatory properties of glucagon-like peptide-1 receptor agonists exendin-4 and lixisenatide. British Journal of Pharmacology 117 (17), pp. 3905 - 3923 (2020)
Journal Article
Poc, P.; Gutzeit, V. A.; Ast, J.; Lee, J.; Jones, B. J.; D´Este, E.; Mathes, B.; Hodson, D. J.; Levitz, J.; Broichhagen, J.: Interrogating surface versus intracellular transmembrane receptor populations using cell-impermeable SNAP-tag substrates. Chemical Science 2020 (30), pp. 7871 - 7883 (2020)
Journal Article
Leippe, P.; Broichhagen, J.; Cailliau, K.; Mougel, A.; Morel, M.; Dissous, C.; Vicogne, J.; Trauner , D.: Transformation of receptor tyrosine kinases into glutamate receptors and photoreceptors. Angewandte Chemie 132 (17), pp. 6786 - 6789 (2020)
Journal Article
Acosta-Ruiz, A.; Gutzeit, V. A.; Skelly, M. J.; Meadows, S.; Lee, J.; Parekh, P.; Orr, A. G.; Liston, C.; Pleil, K. E.; Broichhagen, J. et al.; Levitz, J.: Branched photoswitchable tethered ligands enable ultra-efficient optical control and detection of G protein-coupled receptors in vivo. Neuron 105, pp. 1 - 18 (2020)
Journal Article
Ast, J.; Arvaniti, A.; Fine, N. H.F.; Nasteska, D.; Ashford, F. B.; Stamataki, Z.; Koszegi, Z.; Bacon, A.; Jones, B. J.; Lucey, M. A. et al.; Sasaki, S.; Brierley, D. I.; Hastoy, B.; Tomas, A.; D’Agostino, G.; Reimann, F.; Lynn, F. C.; Reissaus, C. A.; Linnemann, A. K.; D´Este, E.; Calebiro, D.; Trapp, S.; Johnsson, K.; Podewin, T.; Broichhagen, J.; Hodson , D. J.: Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics. Nature Communications 11, 467 (2020), pp. 1 - 18 (2020)
Journal Article
Donthamsetti, P. C.; Broichhagen, J.; Vyklicky, V.; Stanley, C.; Fu, Z.; Visel, M.; Levitz, J. L.; Javitch, J. A.; Trauner, D.; Isacoff, E. Y.: Genetically-targeted optical control of an endogenous G protein-coupled receptor. Journal of the American Chemical Society 141 (29), pp. 11522 - 11530 (2019)
Journal Article
Frank, J. A.; Broichhagen, J.; Yushchenko, D. A.; Trauner, D.; Schultz, C.; Hodson, D. J.: Optical tools for understanding the complexity of β-cell signalling and insulin release. Nature Reviews Endocrinology 14, pp. 721 - 737 (2018)
Journal Article
Ast, J.; Podewin, T.; Arvaniti, A.; Fine, N. H.; Stamataki, Z.; Broichhagen, J.; Johnsson, K.; Hodson, D. J.: Bright and specific far-red labels for visualizing endogenous glucagon-like peptide-1 receptors. Endocrine Abstracts (59), p. P106 (2018)
Journal Article
Farrants, H.; Gutzeit, V. A.; Ruiz, A. A.; Trauner, D.; Johnsson, K.; Levitz, J.; Broichhagen, J.: SNAP-tagged nanobodies enable reversible optical control of a G protein-coupled receptor via a remotely tethered photoswitchable ligand. ACS Chemical Biology 13 (9), pp. 2682 - 2688 (2018)
Journal Article
Karch, S.; Broichhagen, J.; Schneider, J.; Böning, D.; Hartmann, S.; Schmid, B.; Tripal, P.; Palmisano, R.; Alzheimer, C.; Johnsson, K. et al.; Huth, T.: A new fluorogenic small molecule labeling tool for surface diffusion analysis and advanced fluorescence imaging of β-site amyloid precursor protein (APP)-cleaving enzyme 1 based on silicone rhodamine: SiR-BACE1. Journal of Medicinal Chemistry 61 (14), pp. 6121 - 6139 (2018)
Journal Article
Jones, B. J.; Scopelliti, R.; Tomas, A.; Bloom, S. R.; Hodson, D. J.; Broichhagen, J.: Potent prearranged positive allosteric modulators of the glucagon-like peptide-1 receptor. ChemistryOpen 6 (4), pp. 501 - 505 (2017)
Journal Article
Mehta, Z. B.; Johnston, N. R.; Nguyen-Tu, M.-S.; Broichhagen, J.; Schultz, P.; Larner, D. P.; Leclerc, I.; Trauner, D.; Rutter, G. A.; Hodson, D. J.: Remote control of glucose homeostasis in vivo using photopharmacology. Scientific Reports 7, 291, pp. 1 - 11 (2017)

Book Chapter (1)

Book Chapter
Acosta-Ruiz, A.; Broichhagen, J.; Levitz, J.: Optical regulation of class C GPCRs by photoswitchable orthogonal remotely tethered ligands. In: G Protein-Coupled Receptor Signaling, pp. 103 - 136 (Ed. Tiberi, M.). Springer New York, New York, NY (2019)
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