Publications of Rolf Sprengel

Carretero-Guillén, A.; Treviño, M.; Gómez-Climent, M. Á.; Dogbevia, G. K.; Bertocchi, I.; Sprengel, R.; Larkum, M. E.; Vlachos, A.; Gruart, A.; Delgado-García, J. M. et al.; Hasan, M. T.: Dentate gyrus is needed for memory retrieval. Molecular Psychiatry 29 (10), pp. 2939 - 2950 (2024)

Bertocchi, I.; Cifarelli, L.; Oberto, A.; Eva, C. E.; Sprengel, R.; Mirza, N. R.; Muglia, P.: Radiprodil, a selective GluN2B negative allosteric modulator, rescues audiogenic seizures in mice carrying the GluN2A(N615S) mutation. British Journal of Pharmacology 181 (12), pp. 1886 - 1894 (2024)

Strickland, J. A.; Austen, J. M.; Sprengel, R.; Sanderson, D. J.: Knockout of NMDARs in CA1 and dentate gyrus fails to impair temporal control of conditioned behavior in mice. Hippocampus 34 (3), pp. 126 - 140 (2024)

Hjukse, J. B.; Puebla, M. F. D. L.; Vindedal, G. F.; Sprengel, R.; Jensen, V.; Nagelhus, E. A.; Tang, W.: Increased membrane Ca(2+) permeability drives astrocytic Ca(2+) dynamics during neuronal stimulation at excitatory synapses. Glia 71 (12), pp. 2770 - 2781 (2023)

Eltokhi, A.; Bertocchi, I.; Rozov, A.; Jensen, V.; Borchardt, T.; Taylor, A.; Proenca, C. C.; Rawlins, J. N. P.; Bannerman, D. M.; Sprengel, R.: Distinct effects of AMPAR subunit depletion on spatial memory. iScience 26 (11), 108116, pp. 1 - 24 (2023)

Bertocchi, I.; Rocha-Almeida, F.; Romero-Barragán, M. T.; Cambiaghi, M.; Carretero-Guillén, A.; Botta, P.; Dogbevia, G. K.; Treviño, M.; Mele, P.; Oberto, A. et al.; Larkum, M. E.; Gruart, A.; Sprengel, R.; Delgado-García, J. M.; Hasan, M. T.: Pre- and postsynaptic N-methyl-D-aspartate receptors are required for sequential printing of fear memory engrams. iScience 26 (11), 108050, pp. 1 - 22 (2023)

Panayi, M. C.; Boerner, T.; Jahans-Price, T.; Huber, A.; Sprengel, R.; Gilmour, G.; Sanderson, D. J.; Harrison, P. J.; Walton, M. E.; Bannerman, D. M.: Glutamatergic dysfunction leads to a hyper-dopaminergic phenotype through deficits in short-term habituation: a mechanism for aberrant salience. Molecular Psychiatry 28 (2), pp. 579 - 587 (2023)

Austen, J. M.; Sprengel, R.; Sanderson, D. J.: Reinforcement rate and the balance between excitatory and inhibitory learning: insights from deletion of the GluA1 AMPA receptor subunit. Journal of Experimental Psychology: Animal Learning and Cognition 48 (4), pp. 307 - 314 (2022)

Chen-Engerer, H.-J.; Jaeger, S.; Bondarenko, R.; Sprengel, R.; Hengerer, B.; Rosenbrock, H.; Mack, V.; Schuelert, N.: Increasing the excitatory drive rescues excitatory/inhibitory imbalance and mismatch negativity deficit caused by parvalbumin specific GluA1 deletion. Neuroscience 496, pp. 190 - 204 (2022)

Mallien, A. S.; Pfeiffer, N.; Brandwein, C.; Inta, D.; Sprengel, R.; Palme, R.; Talbo, S. R.; Gass, P.: Comparative severity assessment of genetic, stress-based, and pharmacological mouse models of depression. Frontiers in Behavioral Neuroscience 16, 908366, pp. 1 - 14 (2022)

Reiber, M.; Stirling, H.; Sprengel, R.; Gass, P.; Palme, R.; Potschka, H.: Phenotyping young GluA1 deficient mice - a behavioral characterization in a genetic loss-of-function model. Frontiers in Behavioral Neuroscience 16, 877094, pp. 1 - 17 (2022)

Kilonzo, K.; Strahnen, D.; Prex, V.; Gems, J.; van der Veen, B.; Kapanaiah, S. K. T.; Murthy, B. K. B.; Schulz, S.; Sprengel, R.; Bannerman, D. et al.; Kätzel, D.: Distinct contributions of GluA1-containing AMPA receptors of different hippocampal subfields to salience processing, memory and impulse control. Translational Psychiatry 12, 102, pp. 1 - 13 (2022)

Mallien, A. S.; Pfeiffer, N.; Vogt, M. A.; Chourbaji, S.; Sprengel, R.; Gass, P.; Inta, D.: Cre-activation in ErbB4-positive neurons of floxed Grin1/NMDA receptor mice is not associated with major behavioral impairment. Frontiers in Psychiatry 12, 750106, pp. 1 - 12 (2021)

Ang, G.; Brown, L. A.; Tam, S. K. E.; Davies, K. E.; Foster, R. G.; Harrison, P. J.; Sprengel, R.; Vyazovskiy, V. V.; Oliver, P. L.; Bannerman, D. M. et al.; Peirson, S. N.: Deletion of AMPA receptor GluA1 subunit gene (Gria1) causes circadian rhythm disruption and aberrant responses to environmental cues. Translational Psychiatry 11, 588 , pp. 1 - 17 (2021)

Eltokhi, A.; Gonzalez-Lozano, M. A.; Oettl, L.-L.; Rozov, A.; Pitzer, C.; Röth, R.; Berkel, S.; Hüser, M.; Harten, A.; Kelsch, W. et al.; Smit, A. B.; Rappold, G. A.; Sprengel, R.: Imbalanced post- and extrasynaptic SHANK2A functions during development affect social behavior in SHANK2-mediated neuropsychiatric disorders. Molecular Psychiatry 26, pp. 6482 - 6504 (2021)

Austen, J. M.; Pickering, C.; Sprengel, R.; Sanderson, D. J.: Dissociating representations of time and number in reinforcement-rate learning by deletion of the GluA1 AMPA receptor subunit in mice. Psychological Science 32 (2), 956797620960392, pp. 204 - 217 (2021)

Bertocchi, I.; Eltokhi, A.; Rozov, A.; Chi, V. N.; Jensen, V.; Bus, T.; Pawlak, V.; Serafino, M.; Sonntag, H.; Yang, B. et al.; Burnashev, N.; Li, S.-B.; Obenhaus, H. A.; Both, M.; Niewoehner, B.; Single, F. N.; Briese, M.; Boerner, T.; Gass, P.; Rawlins, J. N. P.; Köhr, G.; Bannerman, D. M.; Sprengel, R.: Voltage-independent GluN2A-type NMDA receptor Ca2+ signaling promotes audiogenic seizures, attentional and cognitive deficits in mice. Communications Biology 4, 59 (2021), pp. 1 - 21 (2021)

Austen, J. M.; Sprengel, R.; Sanderson, D. J.: The GluA1 AMPAR subunit is necessary for hedonic responding but not hedonic value in female mice. Physiology & Behavior 228 (1), 113206, pp. 1 - 7 (2021)

Eltokhi, A.; Santuy, A.; Merchan-Perez, A.; Sprengel, R.: Glutamatergic dysfunction and synaptic ultrastructural alterations in schizophrenia and autism spectrum disorder: evidence from human and rodent studies. International Journal of Molecular Sciences 22 (1), 59, pp. 1 - 26 (2020)

Tang, W.; Zillmann, U.; Sprengel, R.: Alternative anesthesia of neonatal mice for global rAAV delivery in the brain with non-detectable behavioral interference in adults. Frontiers in Behavioral Neuroscience 14, 115, pp. 1 - 10 (2020)