Publications of Kristina Haslinger

Peschke, M.; Haslinger, K.; Brieke, C.; Reinstein, J.; Cryle, M. J.: Regulation of the P450 oxygenation cascade involved in glycopeptide antibiotic biosynthesis. Journal of the American Chemical Society 138 (21), pp. 6746 - 6753 (2016)

Brieke, C.; Peschke, M.; Haslinger, K.; Cryle, M. J.: Sequential in vitro cyclization by cytochrome P450 enzymes of glycopeptide antibiotic precursors bearing the X-domain from nonribosomal peptide biosynthesis. Angewandte Chemie International Edition in English 54 (52), pp. 15715 - 15719 (2015)

Haslinger, K.; Peschke, M.; Brieke, C.; Maximowitsch, E.; Cryle, M.: X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis. Nature 521 (7550), pp. 105 - 109 (2015)

Haslinger, K.; Redfield, C.; Cryle, M.: Structure of the terminal PCP domain of the non-ribosomal peptide synthetase in teicoplanin biosynthesis. Proteins: Structure, Function, and Bioinformatics 84 (4), pp. 711 - 721 (2015)

Brieke, C.; Kratzig, V.; Haslinger, K.; Winkler, A.; Cryle, M.: Rapid access to glycopeptide antibiotic precursor peptides coupled with cytochrome P450-mediated catalysis: towards a biomimetic synthesis of glycopeptide antibiotics. Organic & Biomolecular Chemistry 13 (7), pp. 2012 - 2021 (2015)

Haslinger, K.; Maximowitsch, E.; Brieke, C.; Koch, A.; Cryle, M.: Cytochrome P450 OxyBtei catalyzes the first phenolic coupling step in teicoplanin biosynthesis. ChemBioChem: A European Journal of Chemical Biology 15 (18), pp. 2719 - 2728 (2014)

Haslinger, K.; Brieke, C.; Uhlmann, S.; Sieverling, L.; Süssmuth, R. D.; Cryle, M.: The structure of a transient complex of a nonribosomal peptide synthetase and a cytochrome P450 monooxygenase. Angewandte Chemie International Edition: a journal of the Gesellschaft Deutscher Chemiker 53 (32), pp. 8518 - 8522 (2014)

Cryle, M.; Brieke, C.; Haslinger, K.: Oxidative transformations of amino acids and peptides catalysed by cytochromes P450. In: Amino Acids, Peptides and Proteins, Vol. 38, pp. 1 - 36 (Eds. Farkas, E.; Ryadnov , M.). Royal Society of Chemistry, Oxfordshire, UK (2013)

Haslinger, K.: Biochemical and crystallographic characterisation of bacterial Cytochromes P450 involved in the synthesis pathways of natural compounds. Dissertation, 140 pp., Ruprecht-Karls-Universität Heidelberg, Heidelberg (2014)