Publications of Jennifer L. Young

Di Russo, J.; Young, J. L.; Wegner, J. W. R.; Steins, T.; Kessler, H.; Spatz, J. P.: Integrin α5β1 nano-presentation regulates collective keratinocyte migration independent of substrate rigidity. eLife 10, e69861, pp. 1 - 18 (2021)

Elnathan, R.; Holle, A. W.; Young, J. L.; George, M.; Heifler, O.; Goychuk, A.; Frey, E.; Kemkemer, R.; Spatz, J. P.; Kosloff, A. et al.; Patolsky, F.; Voelcker, N.: Optically transparent vertical silicon nanowire arrays for live-cell imaging. Journal of Nanobiotechnology 19 (1), 51 (2021), pp. 1 - 6 (2021)

Wei, Q.; Holle, A. W.; Li, J.; Posa, F.; Biagioni, F.; Croci, O.; Benk, A. S.; Young, J. L.; Noureddine, F.; Deng , J. et al.; Zhang, M.; Inman, G. J.; Spatz, J. P.; Campaner, S.; Cavalcanti-Adam, E. A.: BMP‐2 signaling and mechanotransduction synergize to drive osteogenic differentiation via YAP/TAZ. Advanced Science e-pip (1902931), pp. 1 - 15 (2020)

Yu , L.; Hou, Y.; Xie, W.; Camacho, J. L. C.; Cheng, C.; Holle, A. W.; Young, J. L.; Trappmann, B.; Zhao, W.; Melzig, M. F. et al.; Cavalcanti-Adam, E. A.; Zhao, C.; Spatz, J. P.; Wei, Q.; Haag, R.: Ligand diffusion enables force‐independent cell adhesion via activating α5β1 integrin and initiating rac and RhoA signaling. Advanced Materials (2002566), pp. 1 - 12 (2020)

Young, J. L.; Hua, X.; Somsel, H.; Reichart, F.; Kessler, H.; Spatz, J. P.: Integrin subtypes and nanoscale ligand presentation influence drug sensitivity in cancer cells. Nano Letters 20 (2), pp. 1183 - 1191 (2020)

Kim, C.; Young, J. L.; Holle, A. W.; Jeong, K.; Major, L. G.; Jeong, J. H.; Aman, Z. M.; Han, D.-W.; Hwang, Y.; Spatz, J. P. et al.; Choi, Y. S.: Stem cell mechanosensation on gelatin methacryloyl (GelMA) stiffness gradient hydrogels. Annals of biomedical engineering 48 (2), pp. 893 - 902 (2020)

Wei, Q.; Young, J. L.; Holle, A. W.; Li, J.; Bieback, K.; Inman, G.; Spatz, J. P.; Cavalcanti-Adam, E. A.: Soft hydrogels for balancing cell proliferation and differentiation. ACS Biomaterials Science & Engineering 6 (8), pp. 4687 - 4701 (2020)

Major, L. G.; Holle, A. W.; Young, J. L.; Hepburn, M. S.; Jeong, K.; Chin, I. L.; Sanderson, R. W.; Jeong, J. H.; Aman, Z. M.; Kennedy, B. F. et al.; Hwang, Y.; Han, D.-W.; Park, H. W.; Guan, K.-L.; Spatz, J. P.; Choi, Y. S.: Volume adaptation controls stem cell mechanotransduction. ACS Applied Materials and Interfaces 11 (49), pp. 45520 - 45530 (2019)

Di Russo, J.; Young, J. L.; Balakrishnan , A.; Benk, A. S.; Spatz, J. P.: NTA-Co3+-His6 versus NTA-Ni2+-His6 mediated E-Cadherin surface immobilization enhances cellular traction. Biomaterials, 042, pp. 1 - 24 (2018)

Holle, A. W.; Young, J. L.; Van Vliet, K. J.; Kamm, R. D.; Discher, D.; Janmey, P.; Spatz, J. P.; Saif, T.: Cell–extracellular matrix mechanobiology: forceful tools and emerging needs for basic and translational research. Nano Letters 18 (1), pp. 1 - 8 (2018)

Hadden, W. J.; Young, J. L.; Holle, A. W.; McFetridge, M.; Kim, D. Y.; Wijesinghe, P.; Taylor-Weiner, H.; Wen, J. H.; Lee, A. R.; Bieback, K. et al.; Vo, B.-N.; Sampson, D.; Kennedy, B. F.; Spatz, J. P.; Engler, A. J.; Choi, Y. S.: Stem cell migration and mechanotransduction on linear stiffness gradient hydrogels. Proceedings of the National Academy of Sciences of the United States of America 114 (22), pp. 5647 - 5652 (2017)

Holle, A. W.; McIntyre, A. J.; Kehe, J.; Wijesekara, P.; Young, J. L.; Vincent, L. G.; Engler, A. J.: High content image analysis of focal adhesion-dependent mechanosensitive stem cell differentiation. Integrative Biology 8 (10), pp. 1049 - 1058 (2016)

Young, J. L.; Holle, A. W.; Spatz, J. P.: Nanoscale and mechanical properties of the physiological cell–ECM microenvironment. Experimental Cell Research 343 (1), pp. 3 - 6 (2016)

Holle, A. W.; Young, J. L.; Spatz, J. P.: In vitro cancer cell–ECM interactions inform in vivo cancer treatment. Advanced Drug Delivery Reviews 97, pp. 270 - 279 (2016)