Publications

Bastl, C.; Close, C. M.; Holtz, I.; Gatin-Fraudet, B.; Eis, M.; Werum, M.; Konrad, S.; Kneller, L.; Roßmann, K.; Huhn, C. et al.; Ghosh, S.; Ast, J.; Roosen, D. A.; Lehmann, M.; Haucke, V.; Reymond, L.; Hodson, D. J.; Tinnefeld, P.; Johnsson, K.; Glembockyte, V.; Kilian, N.; Broichhagen, J.: A silicon rhodamine-fused glibenclamide to label and detect malaria-infected red blood cells. Chembiochem, e202400628, pp. 1 - 9 (2025)

Pöschko, P.; Berrou, C. M.; Pakari, K.; Ziegler, M. J.; Kern, C.; Koch, B.; Wittbrodt, J.; Wombacher, R.: Photoactivatable plant hormone-based chemical inducers of proximity for in vivo applications. ACS Chemical Biology 20, pp. 332 - 339 (2025)

Gouveia, G.; Saateh, A.; Swietlikowska, A.; Scarpellini, C.; Tsang, E.; Altug, H.; Merkx, M.; Dillen, A.; Leirs, K.; Spasic, D. et al.; Lammertyn, J.; Gothelf, K. V.; Bonedeau, E.; Porzberg, N.; Smeets, R. L.; Koenen, H. J. P. M.; Prins, M. W. J.; de Jonge, M. I.: Continuous biosensing to monitor acute systemic inflammation, a diagnostic need for therapeutic guidance. ACS Sensors 10 (1), pp. 4 - 14 (2025)

Catapano, C.; Dietz, M. S.; Kompa, J.; Jang, S.; Freund, P.; Johnsson, K.; Heilemann, M.: Long-term single-molecule tracking in living cells using weak-affinity protein labeling. Angewandte Chemie International Edition 64 (1), e202413117, pp. 1 - 8 (2025)

Liu, T.; Kompa, J.; Ling, J.; Lardon, N.; Zhang, Y.; Chen, J.; Reymond, L.; Chen, P.; Tran, M.; Yang, Z. et al.; Zhang, H.; Liu, Y.; Pitsch, S.; Zou, V. O. P.; Wang, L.; Johnsson, K.; Chen, Z.: Gentle rhodamines for live-cell fluorescence microscopy. ACS Central Science 10 (10), pp. 1933 - 1944 (2024)

Kühn, S.; Nasufovic, V.; Wilhelm, J.; Kompa, J.; de Lange, E. M.F.; Lin, Y.-H.; Egoldt, C.; Fischer, J.; Lennoi, A.; Tarnawski, M. et al.; Reinstein, J.; Vlijm, R.; Hiblot, J.; Johnsson, K.: SNAP-tag2: faster and brighter protein labeling. bioRxiv, pp. 1 - 34 (2024)

Wang, M.-M.; Johnsson, K.: Metal-free introduction of primary sulfonamide into electron-rich aromatics. Chemical Science 15 (31), pp. 12310 - 12315 (2024)

Hellweg, L.; Pfeifer, M.; Tarnawski, M.; Thing-Teoh, S.; Chang, L.; Bergner, A.; Kress, J.; Hiblot, J.; Wiedmer, T.; Superti-Furga, G. et al.; Reinhardt, J.; Johnsson, K.; Leippe, P.: AspSnFR: A genetically encoded biosensor for real-time monitoring of aspartate in live cells. Cell Chemical Biology 31 (8), pp. 1529 - 1541.e12 (2024)

Chang, H.; Clemens, S.; Gao, P.; Li, Q.; Zhao, H.; Wang, L.; Zhang, J.; Zhou, P.; Johnsson, K.; Wang, L.: Fluorogenic rhodamine-based chemigenetic biosensor for monitoring cellular NADPH dynamics. Journal of the American Chemical Society 146 (30), pp. 20569 - 20576 (2024)

Neukam, M.; Sala, P.; Brunner, A.-D.; Ganß, K.; Palladini, A.; Grzybek, M.; Topcheva, O.; Vasiljević, J.; Broichhagen, J.; Johnsson, K. et al.; Kurth, T.; Mann, M.; Coskun, Ü.; Solimena, M.: Purification of time-resolved insulin granules reveals proteomic and lipidomic changes during granule aging. Cell Reports 43 (3), 113836, pp. 1 - 23 (2024)

Huppertz, M.-C.; Wilhelm, J.; Grenier, V.; Schneider, M. W.; Falt, T.; Porzberg, N.; Hausmann, D.; Hoffmann, D. C.; Hai, L.; Tarnawski, M. et al.; Pino, G.; Slanchev, K.; Kolb, I.; Acuna, C.; Fenk, L. M.; Baier, H.; Hiblot, J.; Johnsson, K.: Recording physiological history of cells with chemical labeling. Science 383 (6685), pp. 890 - 897 (2024)

Hai, L.; Hoffmann, D. C.; Wagener, R. J.; Azorin, D. D.; Hausmann, D.; Xie, R.; Huppertz, M.-C.; Hiblot, J.; Sievers, P.; Heuer, S. et al.; Ito, J.; Cebulla, G.; Kourtesakis, A.; Kaulen, L. D.; Ratliff, M.; Mandelbaum, H.; Jung, E.; Jabali, A.; Horschitz, S.; Ernst, K. J.; Reibold, D.; Warnken, U.; Venkataramani, V.; Will, R.; Suvà, M. L.; Herold-Mende, C.; Sahm, F.; Winkler, F.; Schlesner, M.; Wick, W.; Kessler, T.: A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1. Nature Communications 15 (1), 968, pp. 1 - 29 (2024)

Relimpio, A. Y.; Fink, A.; Bui, D. T.; Fabritz, S.; Schröter, M.; Ruggieri, A.; Platzman, I.; Spatz, J. P.: Bottom-up assembled synthetic SARS-CoV-2 miniviruses reveal lipid membrane affinity of omicron variant spike glycoprotein. ACS Nano, pp. 23913 - 23923 (2023)

Güldenpfennig, A.; Hopp, A.-K.; Muskalla, L.; Manetsch, P.; Raith, F.; Hellweg, L.; Dördelmann, C.; Pedrioli, D. M. L.; Johnsson, K.; Superti-Furga, G. et al.; Hottiger, M. O.: Absence of mitochondrial SLC25A51 enhances PARP1-dependent DNA repair by increasing nuclear NAD+ levels. Nucleic Acids Research 51 (17), pp. 9248 - 9265 (2023)

Baumgartner, B.; Glembockyte, V.; Mayer, R.; Gonzalez-Hernandez, A.; Kindler, R. O.; Valavalkar, A.; Wiegand, A.; Müller-Deku, A.; Grubert, L.; Steiner, F. et al.; Gross, C.; Reynders, M.; Grenier, V.; Broichhagen, J.; Hecht, S.; Tinnefeld, P.; Ofial, A.; Dietzek-Ivanšic, B.; Levitz, J.; Thorn-Seshold, O.: Azobenzenes can achieve near-infrared photocontrol in biological systems, with quantitative Z→E photoisomerization, via singlet manifold photoredox. ChemRxiv, pp. 1 - 9 (2023)

Hellweg, L.; Edenhofer, A.; Barck, L.; Huppertz, M.-C.; Frei, M. S.; Tarnawski, M.; Bergner, A.; Koch, B.; Johnsson, K.; Hiblot, J.: A general method for the development of multicolor biosensors with large dynamic ranges. Nature Chemical Biology 19 (9), pp. 1147 - 1157 (2023)

Salim, A.; Werther, P.; Hatzopoulos, G. N.; Reymond, L.; Wombacher, R.; Gönczy, P.; Johnsson, K.: Chemical probe for imaging of polo-like Kinase 4 and centrioles. JACS Au 3 (8), pp. 2247 - 2256 (2023)

Jang, S.; Narayanasamy, K. K.; Rahm, J. V.; Saguy, A.; Kompa, J.; Dietz, M. S.; Johnsson, K.; Shechtman, Y.; Heilemann, M.: Neural network-assisted single-molecule localization microscopy with a weak-affinity protein tag. Biophysical Reports 3 (3), 100123, pp. 1 - 9 (2023)

Sahl, S. J.; Matthias, J.; Inamdar, K.; Khan, T. A.; Weber, M.; Becker, S.; Griesinger, C.; Broichhagen, J.; Hell, S. W.: Direct optical measurement of intra-molecular distances down to the Ångström scale. bioRxiv, 548133, pp. 1 - 12 (2023)

Dietl, A.; Wellach, K.; Mahadevan, P.; Mertes, N.; Winter, S. L.; Kutsch, T.; Walz, C.; Schlichting, I.; Fabritz, S.; Barends, T. R. M.: Structures of an unusual 3-hydroxyacyl dehydratase (FabZ) from a ladderane-producing organism with an unexpected substrate preference. The Journal of Biological Chemistry 299 (5), 104602, pp. 1 - 15 (2023)