Publications of Fritjof Helmchen

Helmchen, F.; Denk, W.; Kerr, J.: Miniaturization of two-photon microscopy for imaging in freely moving animals. Cold Spring Harbor Protocols 2013 (10), pp. 904 - 913 (2013)

Lütcke, H.; Murayama, M.; Hahn, T.; Margolis, D. J.; Astori, S.; Meyer zum Alten Borgloh, S.; Göbel, W.; Yang, Y.; Tang, W.; Kügler, S. et al.; Sprengel, R.; Nagai, T.; Miyawaki, A.; Larkum, M. E.; Helmchen, F.; Hasan, M. T.: Optical recording of neuronal activity with a genetically-encoded calcium indicator in anesthetized and freely moving mice. Frontiers in neural circuits 4, 9, pp. 1 - 12 (2010)

Kerr, J.; de Kock, C.; Greenberg, D.; Bruno, R. M.; Sakmann, B.; Helmchen, F.: Spatial organization of neuronal population responses in layer 2/3 of rat barrel cortex. The Journal of Neuroscience 27 (48), pp. 13316 - 13328 (2007)

Larkum, M. E.; Waters, D. J.; Sakmann, B.; Helmchen, F.: Dendritic spikes in apical dendrites of neocortical layer 2/3 pyramidal neurons. The Journal of Neuroscience 27 (34), pp. 8999 - 9008 (2007)

Waters, D. J.; Helmchen, F.: Background synaptic activity is sparse in neocortex. The Journal of Neuroscience: the Official Journal of the Society for Neuroscience 26 (32), pp. 8267 - 8277 (2006)

Helmchen, F.; Denk, W.: Deep tissue two-photon microscopy. Nature methods 2 (12), pp. 932 - 940 (2005)

Kerr, J.; Greenberg, D.; Helmchen, F.: Imaging input and output of neocortical networks in vivo. Proceedings of the National Academy of Sciences of the United States of America 102 (39), pp. 14063 - 14068 (2005)

Sullivan, M. R.; Nimmerjahn, A.; Sarkisov, D. V.; Helmchen, F.; Wang, S. S. H.: In vivo calcium imaging of circuit activity in cerebellar cortex. Journal of Neurophysiology 94 (2), pp. 1636 - 1644 (2005)

Nimmerjahn, A.; Kirchhoff, F.; Helmchen, F.: Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 308 (5726), pp. 1314 - 1318 (2005)

Dittgen, T.; Nimmerjahn, A.; Komai, S.; Licznerski, P.; Waters, D. J.; Margrie, T. W.; Helmchen, F.; Denk, W.; Brecht, M.; Osten, P.: Lentivirus-based genetic manipulations of cortical neurons and their optical and electrophysiological monitoring in vivo. Proceedings of the National Academy of Sciences of the United States of America 101 (52), pp. 18206 - 18211 (2004)

Waters, D. J.; Helmchen, F.: Boosting of action potential backpropagation by neocortical network activity in vivo. The Journal of Neuroscience: the Official Journal of the Society for Neuroscience 24 (49), pp. 11127 - 11136 (2004)

Broser, P. J.; Schulte, R.; Lang, S.; Roth, A.; Helmchen, F.; Waters, D. J.; Sakmann, B.; Wittum, G.: Nonlinear anisotropic diffusion filtering of three-dimensional image data from two-photon microscopy. Journal of Biomedical Optics 9 (6), pp. 1253 - 1264 (2004)

Göbel, W.; Kerr, J.; Nimmerjahn, A.; Helmchen, F.: Miniaturized two-photon microscope based on a flexible coherent fiber bundle and a gradient-index lens objective. Optics Letters 29 (21), pp. 2521 - 2523 (2004)

Brecht, M.; Fee, M. S.; Garaschuk, O.; Helmchen, F.; Margrie, T. W.; Svoboda, K.; Osten, P.: Novel approaches to monitor and manipulate single neurons in vivo. The Journal of Neuroscience: the Official Journal of the Society for Neuroscience 24 (42), pp. 9223 - 9227 (2004)

Nimmerjahn, A.; Kirchhoff, F.; Kerr, J.; Helmchen, F.: Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo. Nature methods 1 (1), pp. 31 - 37 (2004)

Göbel, W.; Nimmerjahn, A.; Helmchen, F.: Distortion-free delivery of nanojoule femtosecond pulses from a Ti:sapphire laser through a hollow-core photonic crystal fiber. Optics Letters 29 (11), pp. 1285 - 1287 (2004)

Kim, J.-H.; Dittgen, T.; Nimmerjahn, A.; Waters, D. J.; Pawlak, V.; Helmchen, F.; Schlesinger, S.; Seeburg, P. H.; Osten, P.: Sindbis vector SINrep(nsP2S726): a tool for rapid heterologous expression with attenuated cytotoxicity in neurons. Journal of Neuroscience Methods 133 (1), pp. 81 - 90 (2004)

Waters, D. J.; Larkum, M. E.; Sakmann, B.; Helmchen, F.: Supralinear Ca²⁺ influx into dendritic tufts of layer 2/3 neocortical pyramidal neurons in vitro and in vivo. The Journal of Neuroscience: the Official Journal of the Society for Neuroscience 23 (24), pp. 8558 - 8567 (2003)

Helmchen, F.: Miniaturization of fluorescence microscopes using fibre optics. Experimental Physiology 87 (6), pp. 737 - 745 (2002)

Helmchen, F.; Denk, W.: New developments in multiphoton microscopy. Current Opinion in Neurobiology 12 (5), pp. 593 - 601 (2002)