Publications of Madeleine Peschke

Rocker, A.; Peschke, M.; Kittilä, T.; Sakson, R.; Brieke, C.; Meinhart, A.: The ng_ζ1 toxin of the gonococcal epsilon/zeta toxin/antitoxin system drains precursors for cell wall synthesis. Nature Communications 9, 1686, pp. 1 - 11 (2018)

Peschke, M.; Brieke, C.; Goode, R. J. A.; Schittenhelm, R. B.; Cryle, M.: Chlorinated glycopeptide antibiotic peptide precursors improve cytochrome P450-catalyzed cyclization cascade efficiency. Biochemistry 56 (9), pp. 1239 - 1247 (2017)

Brieke, C.; Yim, G.; Peschke, M.; Wright, G. D.; Cryle, M. J.: Catalytic promiscuity of glycopeptide N-methyltransferases enables bio-orthogonal labelling of biosynthetic intermediates. Chemical Communications 52 (94), pp. 13679 - 13682 (2016)

Ulrich, V.; Peschke, M.; Brieke, C.; Cryle, M.: More than just recruitment: the X-domain influences catalysis of the first phenolic coupling reaction in A47934 biosynthesis by Cytochrome P450 StaH. Molecular BioSystems 12 (10), pp. 2992 - 3004 (2016)

Peschke, M.; Brieke, C.; Cryle, M. J.: F-O-G ring formation in glycopeptide antibiotic biosynthesis is catalysed by OxyE. Scientific Reports 6, 35584, pp. 1 - 9 (2016)

Peschke, M.; Haslinger, K.; Brieke, C.; Reinstein, J.; Cryle, M. J.: Regulation of the P450 oxygenation cascade involved in glycopeptide antibiotic biosynthesis. Journal of the American Chemical Society 138 (21), pp. 6746 - 6753 (2016)

Brieke, C.; Peschke, M.; Haslinger, K.; Cryle, M. J.: Sequential in vitro cyclization by cytochrome P450 enzymes of glycopeptide antibiotic precursors bearing the X-domain from nonribosomal peptide biosynthesis. Angewandte Chemie International Edition in English 54 (52), pp. 15715 - 15719 (2015)

Haslinger, K.; Peschke, M.; Brieke, C.; Maximowitsch, E.; Cryle, M.: X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis. Nature 521 (7550), pp. 105 - 109 (2015)

Brieke, C.; Kratzig, V.; Peschke, M.; Cryle, M. J.: Facile synthetic access to glycopeptide antibiotic precursor peptides for the investigation of cytochrome P450 action in glycopeptide antibiotic biosynthesis. In: Nonribosomal Peptide and Polyketide Biosynthesis, Vol. 1401, pp. 85 - 102. Springer, New York (2016)

Peschke, M.: In vitro reconstitution of the final steps involved in teicoplanin aglycone production. Dissertation, 198 pp., Ruprecht-Karls-Universität Heidelberg, Heidelberg (2016)