Publications of Frank N. Single

Bertocchi, I.; Eltokhi, A.; Rozov, A.; Chi, V. N.; Jensen, V.; Bus, T.; Pawlak, V.; Serafino, M.; Sonntag, H.; Yang, B. et al.; Burnashev, N.; Li, S.-B.; Obenhaus, H. A.; Both, M.; Niewoehner, B.; Single, F. N.; Briese, M.; Boerner, T.; Gass, P.; Rawlins, J. N. P.; Köhr, G.; Bannerman, D. M.; Sprengel, R.: Voltage-independent GluN2A-type NMDA receptor Ca2+ signaling promotes audiogenic seizures, attentional and cognitive deficits in mice. Communications Biology 4, 59 (2021), pp. 1 - 21 (2021)

Chiu, C.; Reid, C. A.; Heneu, O. T.; Davies, P. J.; Single, F. N.; Koukoulas, I.; Berkovic, S. F.; Tan, S.-S.; Sprengel, R.; Jones, M. V. et al.; Petrou, S.: Developmental impact of a familial GABAA receptor epilepsy mutation. Annals of Neurology 64 (3), pp. 284 - 293 (2008)

Tan, H. O.; Reid, C. A.; Single, F. N.; Davies, P. J.; Chiu, C.; Murphy, S.; Clarke, A. L.; Dibbens, L.; Krestel, H.; Mulley, J. C. et al.; Jones, M. V.; Seeburg, P. H.; Sakmann, B.; Berkovic, S. F.; Sprengel, R.; Petrou, S.: Reduced cortical inhibition in a mouse model of familial childhood absence epilepsy. Proceedings of the National Academy of Sciences of the United States of America 104 (44), pp. 17536 - 17541 (2007)

Niewoehner, B.; Single, F. N.; Hvalby, Ø.; Jensen, V.; Meyer zum Alten Borgloh, S.; Seeburg, P. H.; Rawlins, J. N. P.; Sprengel, R.; Bannerman, D. M.: Impaired spatial working memory but spared spatial reference memory following functional loss of NMDA receptors in the dentate gyrus. European Journal of Neuroscience: European Neuroscience Association 25 (3), pp. 837 - 846 (2007)

Shimshek, D. R.; Bus, T.; Grinevich, V.; Single, F. N.; Mack, V.; Sprengel, R.; Spergel, D. J.; Seeburg, P. H.: Impaired reproductive behavior by lack of GluR-B containing AMPA receptors but not of NMDA receptors in hypothalamic and septal neurons. Molecular Endocrinology 20 (1), pp. 219 - 231 (2006)

Pawlak, V.; Schupp, B.; Single, F. N.; Seeburg, P. H.; Köhr, G.: Impaired synaptic scaling in mouse hippocampal neurons expressing NMDA receptors with reduced calcium permeability. The Journal of Physiology - London 562 (3), pp. 771 - 783 (2005)

Seeburg, P. H.; Single, F. N.; Kuner, T.; Higuchi, M.; Sprengel, R.: Genetic manipulation of key determinants of ion flow in glutamate receptor channels in the mouse. Brain Research 907 (1), pp. 233 - 243 (2001)

Higuchi, M.; Maas, S.; Single, F. N.; Hartner, J. C.; Rozov, A.; Burnashev, N.; Feldmeyer, D.; Sprengel, R.; Seeburg, P. H.: Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2. Nature 406 (6791), pp. 78 - 81 (2000)

Single, F. N.; Rozov, A.; Burnashev, N.; Zimmermann, F.; Hanley, D. F.; Forrest, D.; Curran, T.; Jensen, V.; Hvalby, Ø.; Sprengel, R. et al.; Seeburg, P. H.: Dysfunction in mice by NMDA receptor point mutations NR1(N598Q) and NR1(N598R). The Journal of Neuroscience: the Official Journal of the Society for Neuroscience 20 (7), pp. 2558 - 2566 (2000)

Jerecic, J.; Single, F. N.; Krüth, U.; Krestel, H. E.; Kolhekar, R.; Storck, T.; Kask, K.; Higuchi, M.; Sprengel, R.; Seeburg, P. H.: Studies on conditional gene expression in the brain. Annals of the New York Academy of Sciences 868, pp. 27 - 37 (1999)

Sprengel, R.; Single, F. N.: Mice with genetically modified NMDA and AMPA receptors. Annals of the New York Academy of Sciences 868, pp. 494 - 501 (1999)

Higuchi, M.; Single, F. N.; Köhler, M.; Sommer, B.; Sprengel, R.; Seeburg, P. H.: RNA editing of AMPA receptor subunit GluR-B: A base-paired intron-exon structure determines position and efficiency. Cell 75 (7), pp. 1361 - 1370 (1993)

Sprengel, R.; Eltokhi, A.; Single, F. N.: Gene targeted mice with conditional knock-in (-out) of NMDAR mutations. In: Methods in Molecular Biology, Vol. 1677, pp. 201 - 230 (Eds. Burnashev, N.; Szepetowski, P.). Humana Press, Clifton, N.J. (2017)

Single, F. N.: Transgene Mäuse mit veränderter spannungsabhängiger Ca 2+-Durchlässigkeit des NMDA-Rezeptors. Dissertation, 61 pp., Ruprecht-Karls-Universität Heidelberg, Heidelberg (1999)

Single, F. N.: RNA-editing of AMPA receptor subunit GluR-B: efficiency and specificity. Diploma, 93 pp., Ruprecht-Karls-Universität Heidelberg, Heidelberg (1993)