Publications of Karin Fritz-Wolf

Meinohl, C.; Barnard, S. J.; Fritz-Wolf, K.; Unger, M.; Porr, A.; Heipel, M.; Wirth, S.; Madlung, J.; Nordheim, A.; Menke, A. et al.; Becker, K.; Giehl, K.: Galectin-8 binds to the farnesylated C-terminus of K-Ras4B and modifies Ras/ERK signaling and migration in pancreatic and lung carcinoma cells. Cancers 12 (1), pp. 30 - 54 (2019)

Walter, L.; Sürth, V.; Röttgerding, F.; Zipfel, P. F.; Fritz-Wolf, K.; Kraiczy, P.: Elucidating the immune evasion mechanisms of borrelia mayonii, the causative agent of lyme disease. Frontiers in immunology 10, 2722, pp. 1 - 18 (2019)

Haeussler, K.; Fritz-Wolf, K.; Reichmann, M.; Rahlfs, S.; Becker, K.: Characterization of plasmodium falciparum 6-phosphogluconate dehydrogenase as an antimalarial drug target. Journal of Molecular Biology (London) 430 (21), pp. 4049 - 4067 (2018)

Brandstaedter, C.; Fritz-Wolf, K.; Weder, S.; Fischer, M.; Hecker, B.; Rahlfs, S.; Becker, K.: Kinetic characterization of wild-type and mutant human thioredoxin glutathione reductase defines its reaction and regulatory mechanisms. The FEBS Journal 285 (3), pp. 542 - 558 (2018)

Bathke, J.; Fritz-Wolf, K.; Brandstädter, C.; Burkhardt, A.; Jortzik, E.; Rahlfs, S.; Becker, K.: Structural and functional characterization of Plasmodium falciparum nicotinic acid mononucleotide adenylyltransferase. Journal of Molecular Biology (London) 428 (24, Part B), pp. 4946 - 4961 (2016)

Pretzel, J.; Gehr, M.; Eisenkolb, M.; Wang, L.; Fritz-Wolf, K.; Rahlfs, S.; Becker, K.; Jortzik, E.: Characterization and redox regulation of Plasmodium falciparum methionine adenosyltransferase. The Journal of Biochemistry 160 (6), pp. 355 - 367 (2016)

Wang, L.; Delahunty, C.; Fritz-Wolf, K.; Rahlfs, S.; Prieto, J. H.; Yates, J. R.; Becker, K.: Characterization of the 26S proteasome network in Plasmodium falciparum. Scientific Reports 5, 17818, pp. 1 - 14 (2015)

Mailu, B. M.; Li, L.; Arthur, J.; Nelson, T. M.; Ramasamy, G.; Fritz-Wolf, K.; Becker, K.; Gardner, M. J.: Plasmodium apicoplast Gln-tRNAGln biosynthesis utilizes a unique GatAB amidotransferase essential for erythrocytic stage parasites. The Journal of Biological Chemistry 290 (49), pp. 29629 - 29641 (2015)

Fritz-Wolf, K.; Jortzik, E.; Stumpf, M.; Preuss, J.; Iozef, R.; Rahlfs, S.; Becker, K.: Crystal structure of the Plasmodium falciparum thioredoxin reductase-thioredoxin complex. Journal of Molecular Biology (London) 425 (18), pp. 3446 - 3460 (2013)

Saul, V. V.; de la Vega, L.; Milanovic, M.; Krüger, M.; Braun, T.; Fritz-Wolf, K.; Becker, K.; Schmitz, M. L.: HIPK2 kinase activity depends on cis-autophosphorylation of its activation loop. Journal of molecular cell biology 5 (1), pp. 27 - 38 (2013)

Zocher, K.; Fritz-Wolf, K.; Kehr, S.; Fischer, M.; Rahlfs, S.; Becker, K.: Biochemical and structural characterization of Plasmodium falciparum glutamate dehydrogenase 2. Molecular and Biochemical Parasitology 183 (1), pp. 52 - 62 (2012)

Zocher, K.; Fritz-Wolf, K.; Kehr, S.; Fischer, M.; Rahlfs, S.; Becker, K.: Biochemical and structural characterization of Plasmodium falciparum glutamate dehydrogenase 2. Molecular and Biochemical Parasitology 183 (1), pp. 52 - 62 (2012)

Fritz-Wolf, K.; Kehr, S.; Stumpf, M.; Rahlfs, S.; Becker, K.: Crystal structure of the human thioredoxin reductase-thioredoxin complex. Nature Communications 2, 383, pp. 1 - 8 (2011)

Kasozi, D. M.; Gromer, S.; Adler, H.; Zocher, K.; Rahlfs, S.; Wittlin, S.; Fritz-Wolf, K.; Schirmer, R. H.; Becker, K.: The bacterial redox signaller pyocyanin as an antiplasmodial agent: comparisons with its thioanalog methylene blue. Redox Report 16 (4), pp. 154 - 165 (2011)

Sibbing, D.; Pfeufer, A.; Perisic, T.; Mannes, A. M.; Fritz-Wolf, K.; Unwin, S.; Sinner, M. F.; Gieger, C.; Gloeckner, C. J.; Wichmann, H. E. et al.; Kremmer, E.; Schäfer, Z.; Walch, A.; Hinterseer, M.; Näbauer, M.; Kääb, S.; Kastrati, A.; Schömig, A.; Meitinger, T.; Bornkamm, G. W.; Conrad, M.; von Beckerath, N.: Mutations in the mitochondrial thioredoxin reductase gene TXNRD2 cause dilated cardiomyopathy. European Heart Journal 32 (9), pp. 1121 - 1133 (2011)

Jortzik, E.; Fritz-Wolf, K.; Sturm, N.; Hipp, M.; Rahlfs, S.; Becker, K.: Redox regulation of Plasmodium falciparum ornithine δ-aminotransferase. Journal of Molecular Biology (London) 402 (2), pp. 445 - 459 (2010)

Sturm, N.; Hu, Y.; Zimmermann, H.; Fritz-Wolf, K.; Wittlin, S.; Rahlfs, S.; Becker, K.: Compounds structurally related to ellagic acid show improved intiplasmodial activity. Antimicrobial Agents and Chemotherapy 53 (2), pp. 622 - 630 (2009)

Fritz-Wolf, K.; Urig, S.; Becker, K.: The structure of human thioredoxin reductase 1 provides insights into C-terminal rearrangements during catalysis. Journal of Molecular Biology (London) 370 (1), pp. 116 - 127 (2007)

Bauer, H.; Fritz-Wolf, K.; Winzer, A.; Kühner, S.; Little, S.; Yardley, V.; Vezin, H.; Palfey, B.; Schirmer, R. H.; Davioud−Charvet, E.: A fluoro analogue of the menadione derivative 6-[2'-(3'-methyl)-1',4'-naphthoquinolyl]hexanoic acid is a suicide substrate of glutathione reductase. Crystal structure of the alkylated human enzyme. Journal of the American Chemical Society 128 (33), pp. 10784 - 10794 (2006)

Urig, S.; Fritz-Wolf, K.; Réau, R.; Herold-Mende, C.; Tóth, K.; Davioud-Charvet, E.; Becker, K.: Gold(I)-Phosphinkomplexe für die irreversible Hemmung von humanen Disulfid-Reduktasen. Angewandte Chemie 118 (12), pp. 1915 - 1920 (2006)