Publications

Geyer, M.; Wittinghofer, A.: GEFs, GAPs, GDIs and effectors: taking a closer (3D) look at the regulation of Ras-related GTP-binding proteins. Current Opinion in Structural Biology 7 (6), pp. 786 - 792 (1997)

Schulte, A. C.; Görler, A.; Antz, C.; Neidig, K.-P.; Kalbitzer, H. R.: Use of global symmetries in automated signal class recognition by a bayesian method. Journal of Magnetic Resonance 129 (2), pp. 165 - 172 (1997)

Huxley, H. E.; Holmes, K. C.: Development of synchrotron radiation as a high-intensity source for X-ray diffraction. Journal of Synchrotron Radiation 4 (6), pp. 366 - 379 (1997)

Schlichting, I.; Jung, C.; Schulze, H.: Crystal structure of cytochrome P-450cam complexed with the (1S)-camphor enantiomer. FEBS Letters 415 (3), pp. 253 - 257 (1997)

Ahmadian, M. R.; Stege, P.; Scheffzek, K.; Wittinghofer, A.: Confirmation of the arginine-finger hypothesis for the GAP-stimulated GTP-hydrolysis reaction of Ras. Nature structural biology 4 (9), pp. 686 - 689 (1997)

Geyer, M.; Herrmann, C.; Wohlgemuth, S.; Wittinghofer, A.; Kalbitzer, H. R.: Structure of the Ras-binding domain of RalGEF and implications for Ras binding and signalling. Nature structural biology 4 (9), pp. 694 - 699 (1997)

Schlichting, I.; Reinstein, J.: Structure of active conformations of UMP kinase from Dictyostelium discoideum suggest phosphoryl transfer is associative. Biochemistry 36, pp. 9290 - 9296 (1997)

Lavie, A.; Schlichting, I.; Vetter, I. R.; Konrad, M.; Reinstein, J.; Goody, R. S.: The bottleneck in AZT activation. Nature Medicine 3 (8), pp. 922 - 924 (1997)

Lavie, A.; Vetter, I. R.; Konrad, M.; Goody, R. S.; Reinstein, J.; Schlichting, I.: Structure of thymidylate kinase reveals the cause behind the limiting step in AZT activation. Nature structural biology 4 (8), pp. 601 - 604 (1997)

Scheffzek, K.; Ahmadian, M. R.; Kabsch, W.; Wiesmüller, L.; Lautwein, A.; Schmitz, F.; Wittinghofer, A.: The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants. Science 277 (5324), pp. 333 - 338 (1997)

Wacker-Schröder, I.; Kaether, C.; Kromer, A.; Migala, A.; Almers, W.; Gerdes, H. H.: Microtubule-dependent transport of secretory vesicles visualized in real time with a GFP-tagged secretory protein. Journal of Cell Science 110 (13), pp. 1453 - 1463 (1997)

Wittinghofer, A.; Scheffzek, K.; Ahmadian, M. R.: The interaction of Ras with GTPase-activating proteins. FEBS Letters 410 (1), pp. 63 - 67 (1997)

Schlichting, I.; Berendzen, J.: Out of the blue − the photocycle of the photoactive yellow protein. Structure 5 (6), pp. 735 - 739 (1997)

Lang, T.; Wacker-Schröder, I.; Steyer, J. A.; Kaether, C.; Wunderlich, I.; Soldati, T.; Gerdes, H. H.; Almers, W.: Ca²⁺-triggered peptide secretion in single cells imaged with green fluorescent protein and evanescent-wave microscopy. Neuron 18 (6), pp. 857 - 863 (1997)

Hasson, M. S.; Schlichting, I.; McGowen, M. M.; Woolridge, E. M.; Kozarich, J. W.; Petsko, G. A.; Ringe, D.: Characterization of two crystal forms of 3-carboxy-cis,cis-muconate lactonizing enzyme from Pseudomonas putida. Acta Crystallographica. Section D: Biological Crystallography (Copenhagen) 53 (3), pp. 352 - 353 (1997)

Nordhoff, A.; Tziatzios, C.; van den Broek, J. A.; Schott, M. K.; Kalbitzer, H. R.; Becker, K.; Schubert, D.; Schirmer, R. H.: Denaturation and reactivation of dimeric human glutathione reductase − an assay for folding inhibitors. European Journal of Biochemistry 245 (2), pp. 273 - 282 (1997)

Saijo, Y.; Takeda, S.; Scherer, A.; Kobayashi, T.; Maéda, Y.; Taniguchi, H.; Yao, M.; Wakatsuki, S.: Production, crystallization, and preliminary X-ray analysis of rabbit skeletal muscle troponin complex consisting of troponin C and fragment (1-47) of troponin I. Protein Science 6 (4), pp. 916 - 918 (1997)

Packschies, L.; Theyssen, H.; Buchberger, A.; Bukau, B.; Goody, R. S.; Reinstein, J.: GrpE accelerates nucleotide exchange of the molecular chaperone DnaK with an associative displacement mechanism. Biochemistry 36 (12), pp. 3417 - 3422 (1997)

Schweins, T.; Scheffzek, K.; Assheuer, R.; Wittinghofer, A.: The role of the metal ion in the p21^rascatalysed GTP-hydrolysis: Mn²⁺ versus Mg²⁺. Journal of Molecular Biology (London) 266 (4), pp. 847 - 856 (1997)

Hoffmann, R.; Hoffmann, T.; Tholey, A.; Schulte, A. C.; Kalbitzer, H. R.: Synthesis and NMR spectroscopy of peptides containing either phosphorylated or phosphonylated cis- or trans-4-hydroxi-L-proline. The journal of peptide research 49 (2), pp. 163 - 173 (1997)