Max Planck Institute for Medical Research

Curriculum Vitae Dr. Roman Sarott

Roman Sarott — Roman Sarott

Roman Sarott

Roman Sarott — Roman Sarott

Roman Sarott

Education

2016-2021: Ph.D. in Chemistry, ETH Zürich, Switzerland
2014-2016: Master of Chemistry, ETH Zürich, Switzerland
2010-2013: Bachelor of Chemistry, ETH Zürich, Switzerland

Positions held

since 2025: Max Planck Research Group Leader, Max Planck Institute for Medical Research, Heidelberg, Germany
08/2024 - 12/2024: Founder and Founding Senior Scientist, Shenandoah Therapeutics, San Francisco, USA
11/2021 - 7/2024: SNSF Postdoctoral Research Fellow with Prof. Dr. Nathanael S. Gray, Stanford University, California, USA
11/2016 - 05/2021: Doctoral Studies with Prof. Dr. Erick M. Carreira, ETH Zürich, Switzerland
05/2016 - 09/2016: Medicinal Chemistry Internship, F. Hoffmann La-Roche, Basel, Switzerland
09/2015 - 03/2016: Master Thesis with Prof. Dr. F. Dean Toste, UC Berkeley, California, USA

Scientific Awards and Scholarships

2024: Stanford Cancer Institute Postdoc Fellowship
2022: ETH Medal for Outstanding Dissertations
2022: ACS El Sohly Award for Excellence in Cannabis Chemistry
2022: SNSF Postdoc.Mobility Fellowship

Downloads

Roman Sarott CV 238.6 kB

Selected Publications

Sarott, R. C.; Gourisankar, S.; Karim, B.; Nettles, S.; Yang, H.; Dwyer, B. G.; Simanauskaite, J. M.; Tse, J.; Abuzaid, H.; Krokhotin, A. et al.; Zhang, T.; Hinshaw, S. M. ..; Green, M. R.; Crabtree, G. R.; Gray, N. S.: Relocalizing transcriptional kinases to activate apoptosis. Science 386 (6717), pp. 1 - 9 (2024)

MPG.PuRe

Kosar, M.; Sarott, R. C.; Sykes, D. A.; Viray, A. E. G.; Vitale, R. M.; Tomašević, N.; Li, X.; Ganzoni, R. L. Z.; Kicin, B.; Reichert, L. et al.; Patej, K. J.; Gómez-Bouzó, U.; Guba, W.; McCormick, P. J.; Hua, T.; Gruber, C. W.; Veprintsev, D. B.; Frank, J. A.; Grether, U.; Carreira, E. M.: Flipping the GPCR switch: structure-based development of selective cannabinoid receptor 2 inverse agonists. ACS Central Science 10 (5), pp. 956 - 968 (2024)

MPG.PuRe

Sarott, R. C.; You, I.; Li, Y.-D.; Toenjes, S. T.; Donovan, K. A.; Seo, P.; Ordonez, M.; Byun, W. S.; Hassan, M. M.; Wachter, F. et al.; Chouchani, E. T.; Słabicki, M.; Fischer, E. S.; Ebert, B. L.; Hinshaw, S. M.; Gray, N. S.: Chemical specification of E3 ubiquitin ligase engagement by cysteine-reactive chemistry. Journal of the American Chemical Society 145 (40), pp. 21937 - 21944 (2023)

MPG.PuRe

Sarott, R. C.; Viray, A. E. G.; Pfaff, P.; Sadybekov, A.; Rajic, G.; Katritch, V.; Carreira, E. M.; Frank, J. A.: Optical control of cannabinoid receptor 2-mediated Ca2+ release enabled by synthesis of photoswitchable probes. Journal of the American Chemical Society 143 (2), pp. 736 - 743 (2021)

MPG.PuRe

Sarott, R. C.; Westphal, M. V.; Pfaff, P.; Korn, C.; Sykes, D. A.; Gazzi, T.; Brennecke, B.; Atz, K.; Weise, M.; Mostinski, Y. et al.; Hompluem, P.; Koers, E.; Miljuš, T.; Roth, N. J.; Asmelash, H.; Vong, M. C.; Piovesan, J.; Guba, W.; Rufer, A. C.; Kusznir, E. A.; Huber, S.; Raposo, C.; Zirwes, E. A.; Osterwald, A.; Pavlovic, A.; Moes, S.; Beck, J.; Benito-Cuesta, I.; Grande, T.; de Esteban, S. R. M. N.; Yeliseev, A.; Drawnel, F.; Widmer, G.; Holzer, D.; van der Wel, T.; Mandhair, H.; Yuan, C.-Y.; Drobyski, W. R.; Saroz, Y.; Grimsey, N.; Honer, M.; Fingerle, J.; Gawrisch, K.; Romero, J.; Hillard, C. J.; Varga, Z. V.; van der Stelt, M.; Pacher, P.; Gertsch, J.; McCormick, P. J.; Ullmer, C.; Oddi, S.; Maccarrone, M.; Veprintsev, D. B.; Nazaré, M.; Grether, U.; Carreira, E. M.: Development of high-specificity fluorescent probes to enable cannabinoid type 2 receptor studies in living cells. Journal of the American Chemical Society 142 (40), pp. 16953 - 16964 (2020)

MPG.PuRe